LDLR Protein (AA 22-788) (His-Avi Tag)

Catalog No. ABIN7275139

Product Details

Target: LDLR (Low Density Lipoprotein Receptor (LDLR))

Protein Type: Recombinant

Protein Characteristics: AA 22-788

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This LDLR protein is labelled with His-Avi Tag.

Purpose: Human LDLR Protein

Sequence: Ala22-Arg788

Characteristics: Recombinant Human LDLR Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Ala22-Arg788.

Purity: > 95 % as determined by Tris-Bis PAGE

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1EU per μg by the LAL method.

Biological Activity Comment: The affinity constant of 0.35 nM as determined in SPR assay (Biacore T200). See testing image for detail.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: LDLR (Low Density Lipoprotein Receptor (LDLR))

Alternative Name: LDLR (LDLR Products)

Synonyms: FH Protein, FHC Protein, LDLCQ2 Protein, Hlb301 Protein, LDLRA Protein, LDLA Protein, LDL receptor-2 Protein, fhc Protein, ldlcq2 Protein, ldlr Protein, ldlr2-a Protein, LDL receptor 1 Protein, ldlr-a Protein, ldlr-b Protein, low density lipoprotein receptor Protein, low density lipoprotein receptor a Protein, low density lipoprotein receptor S homeolog Protein, low density lipoprotein receptor L homeolog Protein, LDLR Protein, Ldlr Protein, ldlra Protein, ldlr.S Protein, ldlr.L Protein

Background: The low density lipoprotein receptor (LDLR) is the founding member of the LDL R family of widely expressed cell surface scavenger receptors. It is a cell-surface receptor that recognizes the apoprotein B100 which is embedded in the phospholipid outer layer of LDL particles.

Molecular Weight: 87.6 kDa, Due to glycosylation, the protein migrates to 110-130 kDa based on Tris-Bis PAGE result.

Pathways: Hepatitis C, Lipid Metabolism