Microseminoprotein, Prostate Associated (MSMP) (AA 37-139) protein (Fc Tag)
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- Target See all Microseminoprotein, Prostate Associated (MSMP) Proteins
- Microseminoprotein, Prostate Associated (MSMP)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 37-139
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- Fc Tag
- Purpose
- Mouse PSMP Protein
- Sequence
- Lys37-Ser139
- Characteristics
- Recombinant Mouse PSMP Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Lys37-Ser139.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
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Microseminoprotein, Prostate Associated (MSMP) (AA 37-139) protein (Fc Tag)
MSMP Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Microseminoprotein, Prostate Associated (MSMP) (AA 36-139) protein (His tag)Crystallography grade MSMP Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, Crys, ELISA
Microseminoprotein, Prostate Associated (MSMP) (AA 36-139) protein (His tag)Crystallography grade MSMP Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, Crys, ELISA
Microseminoprotein, Prostate Associated (MSMP) protein (Myc-DYKDDDDK Tag)MSMP Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- Microseminoprotein, Prostate Associated (MSMP)
- Alternative Name
- PSMP (MSMP Products)
- Synonyms
- PSMP Protein, OTTMUSG00000007017 Protein, Psmp Protein, microseminoprotein, prostate associated Protein, MSMP Protein, Msmp Protein
- Background
- PC3-secreted microprotein (PSMP)/microseminoprotein (MSMP) is a novel chemotactic cytokine and its receptor is CCR2. PSMP was highly expressed in fibrotic/cirrhotic tissues from patients with different etiologies of liver disease and in the 3 experimental mouse models of fibrosis. Damage-associated molecular pattern molecules HMGB-1 and IL-33 induced hepatocytes to produce PSMP. PSMP promotes liver fibrosis through inflammatory macrophage infiltration, polarization and production of proinflammatory cytokines, as well as direct activation of hepatic stellate cells via its receptor CCR2.
- Molecular Weight
- 37.9 kDa. Due to glycosylation, the protein migrates to 48-51 kDa based on Tris-Bis PAGE result.
- UniProt
- B1AWI6
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