PLVAP Protein (AA 49-442) (His tag)
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- Target See all PLVAP Proteins
- PLVAP (Plasmalemma Vesicle Associated Protein (PLVAP))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 49-442
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PLVAP protein is labelled with His tag.
- Purpose
- Human PLVAP Protein
- Sequence
- Tyr49-Gly442
- Characteristics
- Recombinant Human PLVAP Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Tyr49-Gly442.
- Purity
- > 95 % as determined by Tris-Bis PAGE
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
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Plasmalemma Vesicle Associated Protein (PLVAP) (AA 51-150) protein (GST tag)
PLVAP Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Plasmalemma Vesicle Associated Protein (PLVAP) (AA 49-442) protein (His tag)Crystallography grade PLVAP Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Plasmalemma Vesicle Associated Protein (PLVAP) (AA 48-438) protein (His tag)Crystallography grade PLVAP Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Plasmalemma Vesicle Associated Protein (PLVAP) (AA 1-442) protein (Strep Tag)Crystallography grade PLVAP Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Plasmalemma Vesicle Associated Protein (PLVAP) (AA 1-438) protein (Strep Tag)Crystallography grade PLVAP Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Plasmalemma Vesicle Associated Protein (PLVAP) protein (Myc-DYKDDDDK Tag)PLVAP Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS, 200 mM L-arginine ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- PLVAP (Plasmalemma Vesicle Associated Protein (PLVAP))
- Alternative Name
- PLVAP (PLVAP Products)
- Synonyms
- MECA32 Protein, Pv1 Protein, FELS Protein, PV-1 Protein, PV1 Protein, gp68 Protein, plasmalemma vesicle associated protein Protein, Plvap Protein, PLVAP Protein
- Background
- Plasmalemma vesicle-associated protein (PLVAP, also called PV-1) is the only protein that forms endothelial diaphragms. PLVAP expression is very low in the normal blood-retinal barrier, however, pathological factors such as high glucose and vascular endothelial growth factor (VEGF) induce its expression, leading to the exacerbation of cellular permeability. Because the new blood vessels are fragile and leaky, PLVAP could possibly be considered a therapeutic target against retinovascular diseases.
- Molecular Weight
- 45.97 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Tris-Bis PAGE result.
- UniProt
- Q9BX97
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