SIGLEC8 Protein (AA 17-363) (Fc Tag)
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- Target See all SIGLEC8 Proteins
- SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 17-363
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SIGLEC8 protein is labelled with Fc Tag.
- Purpose
- Human Siglec-8 Protein
- Sequence
- Met17-Ala363
- Characteristics
- Recombinant Human Siglec-8 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Met17-Ala363.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
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Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) (AA 18-121) protein (GST tag)
SIGLEC8 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) (AA 17-363) protein (His-Avi Tag)SIGLEC8 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) protein (mFc Tag)SIGLEC8 Origin: Human Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) protein (His tag)SIGLEC8 Origin: Human Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) protein (His-Avi Tag,Biotin)SIGLEC8 Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE
Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) (AA 17-363) protein (His tag)Crystallography grade SIGLEC8 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) (AA 385-499) protein (His tag)Crystallography grade SIGLEC8 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) (AA 17-499) protein (rho-1D4 tag)Crystallography grade SIGLEC8 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))
- Alternative Name
- Siglec-8 (SIGLEC8 Products)
- Synonyms
- SAF2 Protein, SIGLEC-8 Protein, SIGLEC8L Protein, SIGLEC8 Protein, sialic acid binding Ig like lectin 8 Protein, sialic acid-binding Ig-like lectin 8 Protein, SIGLEC8 Protein, LOC506364 Protein
- Background
- Siglec-8, also known as SAF, is an approximately 75 kDa transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory molecules. Mature human Siglec-8 consists of a 347 amino acid (aa) extracellular domain (ECD) with three Ig-like domains.Putative adhesion molecule that mediates sialic-acid dependent binding to red blood cells. Preferentially binds to alpha-2,3-linked sialic acid. Also binds to alpha-2,6-linked sialic acid.
- Molecular Weight
- 64.6 kDa. Due to glycosylation, the protein migrates to 70-82 kDa based on Tris-Bis PAGE result.
- UniProt
- Q9NYZ4
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