VLDLR Protein (AA 28-797) (His tag)
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- Target See all VLDLR Proteins
- VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 28-797
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This VLDLR protein is labelled with His tag.
- Purpose
- Mouse VLDLR Protein
- Sequence
- Gly28-Ser797
- Characteristics
- Recombinant Mouse VLDLR Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly28-Ser797.
- Purity
- > 95 % as determined by Tris-Bis PAGE
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- The affinity constant of 0.28 nM as determined in SPR assay (Biacore T200). See testing image for detail.
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Very Low Density Lipoprotein Receptor (VLDLR) (AA 28-797) protein (His tag)
VLDLR Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Very Low Density Lipoprotein Receptor (VLDLR) (AA 28-797) protein (His tag)Crystallography grade VLDLR Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Very Low Density Lipoprotein Receptor (VLDLR) (AA 28-873) protein (rho-1D4 tag)Crystallography grade VLDLR Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Very Low Density Lipoprotein Receptor (VLDLR) (AA 28-769) (Active) protein (His tag)VLDLR Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))
- Alternative Name
- VLDLR (VLDLR Products)
- Synonyms
- CARMQ1 Protein, CHRMQ1 Protein, VLDLRCH Protein, AA408956 Protein, AI451093 Protein, AW047288 Protein, vldlr Protein, very low density lipoprotein receptor Protein, very low density lipoprotein receptor S homeolog Protein, VLDLR Protein, Vldlr Protein, vldlr.S Protein
- Background
- VLDLR cerebellar hypoplasia (VLDLR-CH) is characterized by non-progressive congenital ataxia that is predominantly truncal and results in delayed ambulation, moderate-to-profound intellectual disability, dysarthria, strabismus, and seizures.VLDLR-CH is inherited in an autosomal recessive manner. Carrier testing for at-risk relatives, prenatal testing for a pregnancy at increased risk and preimplantation genetic testing are possible when the pathogenic variants in a family are known.
- Molecular Weight
- 86.1 kDa. Due to glycosylation, the protein migrates to 110-130 kDa based on Tris-Bis PAGE result.
- UniProt
- P98156
- Pathways
- Cellular Response to Molecule of Bacterial Origin
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