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HSV-2 gE Protein (His tag)

This Recombinant HSV-2 gE protein is produced in HEK-293 Cells.
Catalog No. ABIN7448075
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Quick Overview for HSV-2 gE Protein (His tag) (ABIN7448075)

Target

HSV-2 gE (HSV2 gE) (Herpes Simplex Virus Type 2, Glycoprotein E (HSV2 gE))

Protein Type

Recombinant

Origin

Herpes simplex virus type 2

Source

HEK-293 Cells

Purity

90,00 %

Grade

MALS verified
  • Purification tag / Conjugate

    This HSV-2 gE protein is labelled with His tag.

    Purpose

    HSV-2 (HG52) Glycoprotein E Protein, His Tag (MALS verified)

    Sequence

    Ala 21 - Arg 414

    Characteristics

    HSV-2 (HG52) Glycoprotein E, His Tag is expressed from human 293 cells (HEK293). It contains AA Ala 21 - Arg 414 (Accession # P89475).

    Endotoxin Level

    1.0 EU per μg
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  • Comment

    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 45.0 kDa. The protein migrates as 50-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    PBS, pH 7.4

    Storage

    -20 °C

    Storage Comment

    -20°C
  • Target

    HSV-2 gE (HSV2 gE) (Herpes Simplex Virus Type 2, Glycoprotein E (HSV2 gE))

    Alternative Name

    HSV-2 Glycoprotein E

    Target Type

    Viral Protein

    Background

    Synonyms:Glycoprotein E (HSV-2),Description:Herpesvirus infections are widely spread throughout the world population. Herpes simplex virus (HSV) belongs to the α-herpesvirus subfamily. There are two main types of HSV, HSV-1 and HSV-2, which infect humans. HSV-2 mainly causes genital lesions, whereas HSV-1 is involved in both oral and genital infections. In epithelial cells, the heterodimer gE/gI is required for the cell-to-cell spread of the virus, by sorting nascent virions to cell junctions. Once the virus reaches the cell junctions, virus particles can spread to adjacent cells extremely rapidly through interactions with cellular receptors that accumulate at these junctions. Implicated in basolateral spread in polarized cells. In neuronal cells, gE/gI is essential for the anterograde spread of the infection throughout the host nervous system.

    Molecular Weight

    45.0 kDa
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