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IL17B Protein (Biotin,Fc-Avi Tag)

MALS verified IL17B Origin: Human Host: HEK-293 Cells Recombinant 95,00 %
Catalog No. ABIN7448028
  • Target See all IL17B Proteins
    IL17B (Interleukin 17B (IL17B))
    Protein Type
    Recombinant
    Origin
    • 8
    • 3
    • 2
    • 1
    Human
    Source
    • 5
    • 3
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This IL17B protein is labelled with Biotin,Fc-Avi Tag.
    Purpose
    Biotinylated Human IL-17B Protein, Fc,Avitag™ (MALS verified)
    Sequence
    Gln 21 - Phe 180
    Characteristics
    Biotinylated Human IL-17B, Fc,Avitag is expressed from human 293 cells (HEK293). It contains AA Gln 21 - Phe 180 (Accession # Q9UHF5-1).
    Purity
    95,00 %
    Endotoxin Level
    1.0 EU per μg
    Grade
    MALS verified
    Top Product
    Discover our top product IL17B Protein
  • Comment

    This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 45.8 kDa. The protein migrates as 55-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Storage
    -20 °C
    Storage Comment
    -20°C
  • Target
    IL17B (Interleukin 17B (IL17B))
    Alternative Name
    IL-17B (IL17B Products)
    Synonyms
    il-17b Protein, il-20 Protein, zcyto7 Protein, IL17B Protein, IL-17B Protein, IL-20 Protein, NIRF Protein, ZCYTO7 Protein, 1110006O16Rik Protein, 1700006N07Rik Protein, Zcyto7 Protein, interleukin 17B Protein, interleukin 17B L homeolog Protein, IL17B Protein, il17b Protein, il17b.L Protein, Il17b Protein
    Background
    Synonyms:Interleukin-17B,Cytokine Zcyto7,Interleukin-20,IL-20,Neuronal interleukin-17-related factor,IL17B,IL20, NIRF, ZCYTO7,Description:IL-17B is a member of IL17 famaily, was originally described as a proinflammatory cytokine. IL-17B is produced by neutrophils and potentiates TNF-α effect on the production of cytokines and chemokines, such as IL-6, G-CSF, and CCL20, known to control immune cell trafficking to inflamed tissues. Interestingly, although IL-17B and IL-17E (IL-25) share a common receptor, IL-17RB, IL-17B, and IL-17E deficiency lead to opposite results in a model of acute colitis induced by dextran sulfate sodium. IL-17B inhibits IL-17E binding to IL-17RA- IL-17RB complexes on epithelial cells, and limits IL-17E-induced IL-6 production by colon epithelial cells.
    Molecular Weight
    45.8 kDa
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