IL17B Protein (Biotin,Fc-Avi Tag)
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- Target See all IL17B Proteins
- IL17B (Interleukin 17B (IL17B))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IL17B protein is labelled with Biotin,Fc-Avi Tag.
- Purpose
- Biotinylated Human IL-17B Protein, Fc,Avitag™ (MALS verified)
- Sequence
- Gln 21 - Phe 180
- Characteristics
- Biotinylated Human IL-17B, Fc,Avitag is expressed from human 293 cells (HEK293). It contains AA Gln 21 - Phe 180 (Accession # Q9UHF5-1).
- Purity
- 95,00 %
- Endotoxin Level
- 1.0 EU per μg
- Grade
- MALS verified
- Top Product
- Discover our top product IL17B Protein
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- Comment
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This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 45.8 kDa. The protein migrates as 55-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -20 °C
- Storage Comment
- -20°C
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- Target
- IL17B (Interleukin 17B (IL17B))
- Alternative Name
- IL-17B (IL17B Products)
- Synonyms
- il-17b Protein, il-20 Protein, zcyto7 Protein, IL17B Protein, IL-17B Protein, IL-20 Protein, NIRF Protein, ZCYTO7 Protein, 1110006O16Rik Protein, 1700006N07Rik Protein, Zcyto7 Protein, interleukin 17B Protein, interleukin 17B L homeolog Protein, IL17B Protein, il17b Protein, il17b.L Protein, Il17b Protein
- Background
- Synonyms:Interleukin-17B,Cytokine Zcyto7,Interleukin-20,IL-20,Neuronal interleukin-17-related factor,IL17B,IL20, NIRF, ZCYTO7,Description:IL-17B is a member of IL17 famaily, was originally described as a proinflammatory cytokine. IL-17B is produced by neutrophils and potentiates TNF-α effect on the production of cytokines and chemokines, such as IL-6, G-CSF, and CCL20, known to control immune cell trafficking to inflamed tissues. Interestingly, although IL-17B and IL-17E (IL-25) share a common receptor, IL-17RB, IL-17B, and IL-17E deficiency lead to opposite results in a model of acute colitis induced by dextran sulfate sodium. IL-17B inhibits IL-17E binding to IL-17RA- IL-17RB complexes on epithelial cells, and limits IL-17E-induced IL-6 production by colon epithelial cells.
- Molecular Weight
- 45.8 kDa
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