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DENV2 NS1 Protein (His tag)

MALS verified DENV2 NS1 Origin: Dengue Virus Host: HEK-293 Cells Recombinant 95,00 %
Catalog No. ABIN7316943
  • Target See all DENV2 NS1 products
    DENV2 NS1 (Dengue Virus 2 NS1 (DENV2 NS1))
    Protein Type
    Recombinant
    Origin
    Dengue Virus
    Source
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This DENV2 NS1 protein is labelled with His tag.
    Purpose
    DENV2 (strain Thailand/16681/1984) NS1 protein, His Tag (MALS verified)
    Sequence
    Asp 776 - Ala 1127
    Characteristics
    DENV2 (strain Thailand/16681/1984) NS1 protein, His Tag is expressed from human 293 cells (HEK293). It contains AA Asp 776 - Ala 1127 (Accession # P29990-1).
    Purity
    95,00 %
    Endotoxin Level
    1.0 EU per μg
    Grade
    MALS verified
  • Comment

    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 41.8 kDa. The protein migrates as 45-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Storage
    -20 °C
    Storage Comment
    -20°C
  • Target
    DENV2 NS1 (Dengue Virus 2 NS1 (DENV2 NS1))
    Alternative Name
    DENV2 NS1 protein (DENV2 NS1 Products)
    Background
    Synonyms:NS1,Description:Dengue is a mosquito-borne viral disease widely spread all over the world transmitted by 4 serotypes of dengue virus (DENV). The symptoms range from mild dengue fever to dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS) with high mortality. Currently, most of the studies on DENV vaccines emphasize on its envelope protein (i.e., Sanofi's tetravalent dengue vaccine Dengvaxia). However, the fact pointing out that the vaccines with Envelope protein may could have negative effect on people never infected by DENV which makes the non-structural protein NS1 become another great target for vaccine research with its ability to avoid Antibody Dependent Enhancement.
    Molecular Weight
    41.8 kDa
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