IGFBP7 Protein (His tag)
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- Target See all IGFBP7 Proteins
- IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IGFBP7 protein is labelled with His tag.
- Sequence
- Ser27-Leu282
- Characteristics
- Recombinant Human IGFBP-7 Protein Protein is expressed from Expi293 with His tag at the N-terminal.It contains Ser27-Leu282.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human IGFBP-7, His Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Human CD93, hFc Tag with the EC50 of 0.74μg/ml determined by ELISA. See testing image for detail.
- Top Product
- Discover our top product IGFBP7 Protein
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Insulin-Like Growth Factor Binding Protein 7 (IGFBP7) (AA 26-281) protein (His tag)
IGFBP7 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Insulin-Like Growth Factor Binding Protein 7 (IGFBP7) (AA 27-282) protein (His tag)IGFBP7 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Insulin-Like Growth Factor Binding Protein 7 (IGFBP7) (AA 27-282) protein (His tag)Crystallography grade IGFBP7 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Insulin-Like Growth Factor Binding Protein 7 (IGFBP7) (AA 26-281) protein (His tag)Crystallography grade IGFBP7 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 5 % trehalose is added as protectant before lyophilization.
- Storage
- 4 °C,-80 °C
- Storage Comment
- Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
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- Target
- IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))
- Alternative Name
- IGFBP-7 (IGFBP7 Products)
- Synonyms
- zgc:85888 Protein, AGM Protein, FSTL2 Protein, IBP-7 Protein, IGFBP-7 Protein, IGFBP-7v Protein, IGFBPRP1 Protein, MAC25 Protein, PSF Protein, RAMSVPS Protein, TAF Protein, Fstl2 Protein, Mac25 Protein, insulin like growth factor binding protein 7 Protein, insulin-like growth factor binding protein 7 Protein, IGFBP7 Protein, igfbp7 Protein, Igfbp7 Protein
- Background
- IGFBP-7, IBP7, AGM, FSTL2, IGFBP-7v, IGFBPRP1, MAC25, PSF, RAMSVPS, TAF. IGFBP-7, also known as Mac25/Angiomodulin (AGM), GFBP-rp1, tumor-derived adhesion factor (TAF) and prostacyclin-stimulating factor (PSF), is a secreted protein that contains three protein domain modules. Human IGFBP-rp1 cDNA encodes 282 amino acid (aa) residue precursor protein with a putative 26 aa signal peptide. IGFBP-7 binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion.
- Molecular Weight
- 27.5 kDa. Due to glycosylation, the protein migrates to 35-40 kDa based on Tris-Bis PAGE result.
- UniProt
- Q16270
- Pathways
- Growth Factor Binding
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