IL18BP Protein (AA 28-207) (Biotin,His tag)
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- Target See all IL18BP Proteins
- IL18BP (Interleukin 18 Binding Protein (IL18BP))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 28-207
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Origin
- Cynomolgus
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IL18BP protein is labelled with Biotin,His tag.
- Purpose
- Biotinylated Cynomolgus IL-18BP Protein (Primary Amine Labeling)
- Sequence
- Thr28-Pro207
- Characteristics
- Recombinant Biotinylated Cynomolgus IL-18BP Protein (Primary Amine Labeling) is expressed from HEK293 with His tag at the C-Terminus.It contains Thr28-Pro207.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- The affinity constant of 1.67 nM as determined in SPR assay (Biacore T200). See testing image for detail.
- Top Product
- Discover our top product IL18BP Protein
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Interleukin 18 Binding Protein (IL18BP) (AA 31-194) protein (Fc Tag)
IL18BP Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Interleukin 18 Binding Protein (IL18BP) (AA 31-194) protein (His tag)IL18BP Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Interleukin 18 Binding Protein (IL18BP) (AA 31-194) protein (His-Avi Tag,Biotin)IL18BP Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 18 Binding Protein (IL18BP) (AA 29-193) protein (His tag)IL18BP Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 18 Binding Protein (IL18BP) (AA 29-193) protein (Fc Tag)IL18BP Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 18 Binding Protein (IL18BP) (AA 31-194) protein (GST tag)IL18BP Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied as 0.22μm filtered solution in PBS ( pH 7.4).
- Storage
- -80 °C
- Storage Comment
- Valid for 12 months from date of receipt when stored at -80°C.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- IL18BP (Interleukin 18 Binding Protein (IL18BP))
- Alternative Name
- IL-18BP (IL18BP Products)
- Synonyms
- IL18BP Protein, IL-18BP Protein, Igifbp Protein, MC54L Protein, IL18BPa Protein, interleukin 18 binding protein Protein, IL18BP Protein, Il18bp Protein
- Background
- Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway are upregulated on tumour-infiltrating lymphocytes, suggesting that IL-18 therapy could enhance anti-tumour immunity. IL-18BP, a high-affinity IL-18 decoy receptor, is frequently upregulated in diverse human and mouse tumours and limits the anti-tumour activity of IL-18 in mice.
- Molecular Weight
- 21.14 kDa. Due to glycosylation, the protein migrates to 50-65 kDa based on Tris-Bis PAGE result.
- UniProt
- A0A2K5UDJ4
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