IL-37 Protein (AA 27-192)
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- Target See all IL-37 (IL37) Proteins
- IL-37 (IL37) (Interleukin 37 (IL37))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 27-192
- Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purpose
- Human IL-37 Protein
- Sequence
- Lys27-Asp192
- Characteristics
- Recombinant Human IL-37 Protein is expressed from E.coli without tag.It contains Lys27-Asp192.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- The affinity constant of 0.12 μM as determined in SPR assay (Biacore T200). See testing image for detail.
- Top Product
- Discover our top product IL37 Protein
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Interleukin 37 (IL37) (AA 1-218) protein (GST tag)
IL37 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 37 (IL37) (Active) proteinIL37 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Interleukin 37 (IL37) (AA 46-218) protein (His tag)Crystallography grade IL37 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Interleukin 37 (IL37) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)IL37 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in 20 mM PBS, 2 mM DTT ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Preservative
- Dithiothreitol (DTT)
- Precaution of Use
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- IL-37 (IL37) (Interleukin 37 (IL37))
- Alternative Name
- IL-37 (IL37 Products)
- Synonyms
- FIL1 Protein, FIL1(ZETA) Protein, FIL1Z Protein, IL-1F7 Protein, IL-1H Protein, IL-1H4 Protein, IL-1RP1 Protein, IL-37 Protein, IL1F7 Protein, IL1H4 Protein, IL1RP1 Protein, interleukin 37 Protein, IL37 Protein
- Background
- IL-37 is a unique member of the IL-1 family of cytokines, which functions as a natural suppressor of inflammatory and immune responses. Immune and non-immune cells produce IL-37 precursor following pro-inflammatory stimuli. Following activating cleavage by caspase-1, mature IL-37 translocates to the nucleus, where it suppresses transcription of pro-inflammatory genes.
- Molecular Weight
- 18.55 kDa same as Tris-Bis PAGE result.
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