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NG2 Protein (AA 1581-2222) (His tag)

MCSP Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7454185
  • Target See all NG2 (MCSP) Proteins
    NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1581-2222
    Origin
    • 5
    • 3
    Cynomolgus
    Source
    • 7
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This NG2 protein is labelled with His tag.
    Purpose
    Cynomolgus CSPG4/MCSP Protein
    Sequence
    Ser1581-Ser2222
    Characteristics
    Recombinant Cynomolgus CSPG4/MCSP Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser1581-Ser2222.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product MCSP Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))
    Alternative Name
    CSPG4 (MCSP Products)
    Synonyms
    HMW-MAA Protein, MCSP Protein, MCSPG Protein, MEL-CSPG Protein, MSK16 Protein, NG2 Protein, 4732461B14Rik Protein, AN2 Protein, Ng2 Protein, HSMCSGEN1 Protein, MCS Protein, chondroitin sulfate proteoglycan 4 Protein, sperm mitochondria associated cysteine rich protein Protein, CSPG4 Protein, Cspg4 Protein, SMCP Protein
    Background
    The chondroitin sulfate proteoglycan-4 (CSPG4) is a cell surface proteoglycan overexpressed in a huge range of human and canine neoplastic lesions by tumor cells, tumor microenvironment and cancer initiating cells. CSPG4 plays a central role in the oncogenic pathways required for malignant progression and metastatization.
    Molecular Weight
    69.30 kDa. Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.
    UniProt
    A0A2K5UW71
    Pathways
    Glycosaminoglycan Metabolic Process
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