NG2 Protein (AA 1581-2222) (His tag)
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- Target See all NG2 (MCSP) Proteins
- NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1581-2222
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Origin
- Cynomolgus
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This NG2 protein is labelled with His tag.
- Purpose
- Cynomolgus CSPG4/MCSP Protein
- Sequence
- Ser1581-Ser2222
- Characteristics
- Recombinant Cynomolgus CSPG4/MCSP Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser1581-Ser2222.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product MCSP Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))
- Alternative Name
- CSPG4 (MCSP Products)
- Synonyms
- HMW-MAA Protein, MCSP Protein, MCSPG Protein, MEL-CSPG Protein, MSK16 Protein, NG2 Protein, 4732461B14Rik Protein, AN2 Protein, Ng2 Protein, HSMCSGEN1 Protein, MCS Protein, chondroitin sulfate proteoglycan 4 Protein, sperm mitochondria associated cysteine rich protein Protein, CSPG4 Protein, Cspg4 Protein, SMCP Protein
- Background
- The chondroitin sulfate proteoglycan-4 (CSPG4) is a cell surface proteoglycan overexpressed in a huge range of human and canine neoplastic lesions by tumor cells, tumor microenvironment and cancer initiating cells. CSPG4 plays a central role in the oncogenic pathways required for malignant progression and metastatization.
- Molecular Weight
- 69.30 kDa. Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.
- UniProt
- A0A2K5UW71
- Pathways
- Glycosaminoglycan Metabolic Process
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