NEO1 Protein (AA 34-1105) (Fc Tag)
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- Target See all NEO1 Proteins
- NEO1 (Neogenin 1 (NEO1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 34-1105
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This NEO1 protein is labelled with Fc Tag.
- Purpose
- Human Neogenin Protein
- Sequence
- Ala34-Leu1105
- Characteristics
- Recombinant Human Neogenin Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ala34-Leu1105.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human RGMa, His Tag at 5μg/ml (100μl/Well) on the plate. Dose response curve for Human Neogenin, hFc Tag with the EC50 of 0.45μg/ml determined by ELISA. See testing image for detail.
- Top Product
- Discover our top product NEO1 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- NEO1 (Neogenin 1 (NEO1))
- Alternative Name
- Neogenin (NEO1 Products)
- Synonyms
- cb333 Protein, zneo1 Protein, zgc:109795 Protein, 2610028H22Rik Protein, AI327052 Protein, D930014N22Rik Protein, Igdcc2 Protein, IGDCC2 Protein, NGN Protein, neogenin 1a Protein, neogenin 1 Protein, neogenin Protein, neo1a Protein, NEO1 Protein, LOC100448839 Protein, Neo1 Protein
- Background
- Neogenin is a multifunctional transmembrane receptor belonging to the immunoglobulin superfamily. It displays identical secondary structure to deleted in colorectal cancer (DCC), a netrin receptor that is involved in axon guidance and cell survival.
- Molecular Weight
- 144.37 kDa. Due to glycosylation, the protein migrates to 150-180 kDa based on Tris-Bis PAGE result.
- Pathways
- Transition Metal Ion Homeostasis, Regulation of Muscle Cell Differentiation, Tube Formation
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