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Vitronectin Protein (VTN) (AA 20-478) (His tag)

VTN Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7454232
  • Target See all Vitronectin (VTN) Proteins
    Vitronectin (VTN)
    Protein Type
    Recombinant
    Protein Characteristics
    AA 20-478
    Origin
    • 16
    • 5
    • 1
    • 1
    • 1
    Human
    Source
    • 9
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Vitronectin protein is labelled with His tag.
    Purpose
    Human Vitronectin Protein
    Sequence
    Asp20-Leu478
    Characteristics
    Recombinant Human Vitronectin Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Asp20-Leu478.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Human Vitronectin, His Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Mouse ITGAV&ITGB3, His Tag with the EC50 of 0.30μng/ml determined by ELISA. See testing image for detail.
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    Discover our top product VTN Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    Vitronectin (VTN)
    Alternative Name
    Vitronectin (VTN Products)
    Synonyms
    VTN Protein, DKFZp470F0511 Protein, LOC100228142 Protein, vtn Protein, zgc:112277 Protein, V75 Protein, VN Protein, VNT Protein, AI256434 Protein, Vn Protein, Aa1018 Protein, vitronectin Protein, vitronectin a Protein, vitronectin b Protein, vitronectin L homeolog Protein, VTN Protein, vtn Protein, vtna Protein, vtnb Protein, CpipJ_CPIJ016691 Protein, vtn.L Protein, Vtn Protein
    Background
    Vitronectin is a multifunctional glycoprotein present in blood and in the extracellular matrix. It binds glycosaminoglycans, collagen, plasminogen and the urokinase-receptor, and also stabilizes the inhibitory conformation of plasminogen activation inhibitor-1.
    Molecular Weight
    53.37 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
    UniProt
    P04004
    Pathways
    Autophagy, Smooth Muscle Cell Migration
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