BTK Protein (DYKDDDDK Tag)
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- Target See all BTK Proteins
- BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This BTK protein is labelled with DYKDDDDK Tag.
- Purpose
- Recombinant Human BTK Protein with C-terminal 3xFlag tag
- Specificity
- BTK (Met1-Ser659) 3xFlag tag
- Characteristics
- Extracellular Domain Protein
- Purity
- The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product BTK Protein
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Bruton Agammaglobulinemia tyrosine Kinase (BTK) (AA 1-659) protein (GST tag)
BTK Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Bruton Agammaglobulinemia tyrosine Kinase (BTK) (AA 100-189) protein (GST tag)BTK Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Bruton Agammaglobulinemia tyrosine Kinase (BTK) (AA 2-659) protein (His tag)Crystallography grade BTK Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Bruton Agammaglobulinemia tyrosine Kinase (BTK) (AA 2-659) protein (His tag)Crystallography grade BTK Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))
- Alternative Name
- BTK (BTK Products)
- Synonyms
- BTK Protein, atk Protein, bpk Protein, xla Protein, imd1 Protein, agmx1 Protein, psctk1 Protein, AGMX1 Protein, AT Protein, ATK Protein, BPK Protein, IMD1 Protein, PSCTK1 Protein, XLA Protein, AI528679 Protein, xid Protein, Bruton tyrosine kinase Protein, Bruton agammaglobulinemia tyrosine kinase Protein, BTK Protein, btk Protein, Btk Protein
- Background
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AGMX1, AT, ATK, BPK, IGHD3, IMD1, PSCTK1, XLA
Description: The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013] - Molecular Weight
- predicted molecular mass of 79.2 kDa after removal of the signal peptide.
- UniProt
- Q06187
- Pathways
- Fc-epsilon Receptor Signaling Pathway, Hormone Transport, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, BCR Signaling
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