SPA17 Protein (His tag)
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- Target See all SPA17 Proteins
- SPA17 (Sperm Autoantigenic Protein 17 (SPA17))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SPA17 protein is labelled with His tag.
- Purpose
- Recombinant Human SPA17 Protein with C-terminal 6xHis tag
- Specificity
- SPA17 (Met1-Lys151) 6xHis tag
- Characteristics
- Extracellular Domain Protein
- Purity
- The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product SPA17 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- SPA17 (Sperm Autoantigenic Protein 17 (SPA17))
- Alternative Name
- SPA17 (SPA17 Products)
- Synonyms
- spa17 Protein, MGC89454 Protein, SPA17 Protein, CT22 Protein, SP17 Protein, SP17-1 Protein, Sp17 Protein, sperm autoantigenic protein 17 Protein, sperm autoantigenic protein 17 L homeolog Protein, spa17 Protein, SPA17 Protein, spa17.L Protein, Spa17 Protein
- Background
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CT22, SP17, SP17-1
Description: This gene encodes a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22.[provided by RefSeq, Jan 2009] - Molecular Weight
- predicted molecular mass of 18.2 kDa after removal of the signal peptide. The apparent molecular mass of SPA17-His is 15-25 kDa due to glycosylation.
- UniProt
- Q15506
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