ACVR1C/ALK7 Protein (Fc Tag)
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- Target See all ACVR1C/ALK7 (ACVR1C) Proteins
- ACVR1C/ALK7 (ACVR1C) (Activin Receptor Type 1C (ACVR1C))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ACVR1C/ALK7 protein is labelled with Fc Tag.
- Purpose
- Recombinant Human ACVR1C Protein with C-terminal human Fc tag
- Specificity
- ACVR1C (Leu22-Glu113) hFc (Glu99-Ala330)
- Characteristics
- Extracellular Domain Protein
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product ACVR1C Protein
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Activin Receptor Type 1C (ACVR1C) (AA 1-493) protein (GST tag)
ACVR1C Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Activin Receptor Type 1C (ACVR1C) (AA 23-112) protein (GST tag)ACVR1C Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Activin Receptor Type 1C (ACVR1C) (AA 135-493) protein (His tag)Crystallography grade ACVR1C Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Activin Receptor Type 1C (ACVR1C) (AA 135-493) protein (His tag)Crystallography grade ACVR1C Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Activin Receptor Type 1C (ACVR1C) (AA 21-493) protein (rho-1D4 tag)Crystallography grade ACVR1C Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Activin Receptor Type 1C (ACVR1C) (AA 26-493) protein (rho-1D4 tag)Crystallography grade ACVR1C Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Activin Receptor Type 1C (ACVR1C) (AA 21-113) protein (His tag)ACVR1C Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
Activin Receptor Type 1C (ACVR1C) (Transcript Variant 4) protein (Myc-DYKDDDDK Tag)ACVR1C Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- ACVR1C/ALK7 (ACVR1C) (Activin Receptor Type 1C (ACVR1C))
- Alternative Name
- ACVR1C (ACVR1C Products)
- Synonyms
- ACVRLK7 Protein, ALK7 Protein, Alk-7 Protein, C230097P10 Protein, Alk7 Protein, habrec1 Protein, activin A receptor type 1C Protein, activin A receptor, type IC Protein, ACVR1C Protein, Acvr1c Protein
- Background
- ACVRLK7, ALK7ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM, Mar 2008]
- Molecular Weight
- predicted molecular mass of 36.0 kDa after removal of the signal peptide. The apparent molecular mass of ACVR1C-hFc is 35-70 kDa due to glycosylation.
- UniProt
- Q8NER5
- Pathways
- Negative Regulation of Hormone Secretion, Positive Regulation of Endopeptidase Activity
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