RHOB Protein (Fc Tag)
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- Target See all RHOB Proteins
- RHOB (Ras Homolog Gene Family, Member B (RHOB))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This RHOB protein is labelled with Fc Tag.
- Purpose
- Recombinant Human RHOB Protein with C-terminal human Fc tag
- Specificity
- RHOB (Met1-Gly188) hFc (Glu99-Ala330)
- Characteristics
- Extracellular Domain Protein
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product RHOB Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- RHOB (Ras Homolog Gene Family, Member B (RHOB))
- Alternative Name
- RHOB (RHOB Products)
- Synonyms
- ARH6 Protein, ARHB Protein, MST081 Protein, MSTP081 Protein, RHOH6 Protein, AA017882 Protein, Arh6 Protein, Arhb Protein, RHO Protein, arha Protein, rhoa Protein, wu:fj42e08 Protein, zgc:92206 Protein, rhob Protein, xrhob Protein, ras homolog family member B Protein, ras homolog gene family, member Ab Protein, ras homolog family member B S homeolog Protein, RHOB Protein, Rhob Protein, rhoab Protein, rhob.S Protein
- Background
- ARH6, ARHB, MST081, MSTP081, RHOH6Mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells.[UniProtKB/Swiss-Prot Function]
- Molecular Weight
- predicted molecular mass of 47.4 kDa after removal of the signal peptide. The apparent molecular mass of RHOB-hFc is 35-55 kDa due to glycosylation.
- UniProt
- P62745
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