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RHOB Protein (Fc Tag)

RHOB Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Catalog No. ABIN7491409
  • Target See all RHOB Proteins
    RHOB (Ras Homolog Gene Family, Member B (RHOB))
    Protein Type
    Recombinant
    Origin
    • 6
    • 1
    • 1
    • 1
    Human
    Source
    • 2
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This RHOB protein is labelled with Fc Tag.
    Purpose
    Recombinant Human RHOB Protein with C-terminal human Fc tag
    Specificity
    RHOB (Met1-Gly188) hFc (Glu99-Ala330)
    Characteristics
    Extracellular Domain Protein
    Purity
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product RHOB Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    RHOB (Ras Homolog Gene Family, Member B (RHOB))
    Alternative Name
    RHOB (RHOB Products)
    Synonyms
    ARH6 Protein, ARHB Protein, MST081 Protein, MSTP081 Protein, RHOH6 Protein, AA017882 Protein, Arh6 Protein, Arhb Protein, RHO Protein, arha Protein, rhoa Protein, wu:fj42e08 Protein, zgc:92206 Protein, rhob Protein, xrhob Protein, ras homolog family member B Protein, ras homolog gene family, member Ab Protein, ras homolog family member B S homeolog Protein, RHOB Protein, Rhob Protein, rhoab Protein, rhob.S Protein
    Background
    ARH6, ARHB, MST081, MSTP081, RHOH6Mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells.[UniProtKB/Swiss-Prot Function]
    Molecular Weight
    predicted molecular mass of 47.4 kDa after removal of the signal peptide. The apparent molecular mass of RHOB-hFc is 35-55 kDa due to glycosylation.
    UniProt
    P62745
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