MRGPRX2 Protein (Fc Tag)
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- Target See all MRGPRX2 Proteins
- MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This MRGPRX2 protein is labelled with Fc Tag.
- Purpose
- Recombinant Human MRGPRX2 Protein with C-terminal human Fc tag
- Specificity
- MRGPRX2 (Met1-Pro33) hFc (Glu99-Ala330)
- Characteristics
- Extracellular Domain Protein
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product MRGPRX2 Protein
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G Protein-Coupled Receptor MRGX2 (MRGPRX2) (AA 1-330) protein (GST tag)
MRGPRX2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
G Protein-Coupled Receptor MRGX2 (MRGPRX2) (AA 1-330) protein (Strep Tag)Crystallography grade MRGPRX2 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
G Protein-Coupled Receptor MRGX2 (MRGPRX2) (AA 1-352) protein (Strep Tag)Crystallography grade MRGPRX2 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))
- Alternative Name
- MRGPRX2 (MRGPRX2 Products)
- Synonyms
- MRGX2 Protein, G370024M05Rik Protein, MrgB10 Protein, Mrgprb10 Protein, MrgB1 Protein, Mrgprb1 Protein, MAS related GPR family member X2 Protein, MAS-related GPR, member X2 Protein, MRGPRX2 Protein, Mrgprx2 Protein
- Background
- MGRG3, MRGX2Mast cell-specific receptor for basic secretagogues, i.e. cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core (PubMed:25517090). Recognizes and binds small molecules containing a cyclized tetrahydroisoquinoline (THIQ), such as non-steroidal neuromuscular blocking drugs (NMBDs), including tubocurarine and atracurium. In response to these compounds, mediates pseudo-allergic reactions characterized by histamine release, inflammation and airway contraction (By similarity). Acts as a receptor for a number of other ligands, including peptides and alkaloids, such as cortistatin-14, proadrenomedullin N-terminal peptides PAMP-12 and, at lower extent, PAMP-20, antibacterial protein LL-37, PMX-53 peptide, beta-defensins, and complanadine A.[UniProtKB/Swiss-Prot Function]
- Molecular Weight
- predicted molecular mass of 29.6 kDa after removal of the signal peptide. The apparent molecular mass of MRGPRX2-hFc is 35-55 kDa due to glycosylation.
- UniProt
- Q96LB1
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