GLP1R Protein (Fc Tag)
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- Target See all GLP1R Proteins
- GLP1R (Glucagon-Like Peptide 1 Receptor (GLP1R))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This GLP1R protein is labelled with Fc Tag.
- Purpose
- Recombinant Human GLP1R Protein with C-terminal human Fc tag
- Specificity
- GLP1R (Arg24-Glu139) hFc (Glu99-Ala330)
- Characteristics
- Extracellular Domain Protein
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product GLP1R Protein
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Glucagon-Like Peptide 1 Receptor (GLP1R) (AA 22-145) protein (His tag)
GLP1R Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Glucagon-Like Peptide 1 Receptor (GLP1R) (AA 24-145) protein (His tag)GLP1R Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Glucagon-Like Peptide 1 Receptor (GLP1R) (AA 24-145), (Extracellular) protein (His tag)GLP1R Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- GLP1R (Glucagon-Like Peptide 1 Receptor (GLP1R))
- Alternative Name
- GLP1R (GLP1R Products)
- Synonyms
- GLP1R Protein, LOC100228311 Protein, GLP-1R Protein, GLP1Rc Protein, Glip Protein, RATGL1RCP Protein, glucagon like peptide 1 receptor Protein, glucagon-like peptide 1 receptor Protein, GLP1R Protein, Glp1r Protein
- Background
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GLP-1, GLP-1-R, GLP-1R
Description: This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016] - Molecular Weight
- predicted molecular mass of 39.7 kDa after removal of the signal peptide. The apparent molecular mass of GLP1R-hFc is 35-70 kDa due to glycosylation.
- UniProt
- P43220
- Pathways
- Positive Regulation of Peptide Hormone Secretion, Hormone Transport, cAMP Metabolic Process, Feeding Behaviour
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