GPR75 Protein
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- Target See all GPR75 Proteins
- GPR75 (G Protein-Coupled Receptor 75 (GPR75))
- Protein Type
- Synthetic
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Origin
- Human
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Source
- HEK-293 Cells
- Purpose
- Human GPR75 full length protein-synthetic nanodisc
- Characteristics
- Full Length Transmembrane Proteins (synthetic Nanodisc)
- Top Product
- Discover our top product GPR75 Protein
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G Protein-Coupled Receptor 75 (GPR75) (AA 372-540) protein (His tag)
Crystallography grade GPR75 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
G Protein-Coupled Receptor 75 (GPR75) (AA 372-540) protein (His tag)Crystallography grade GPR75 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
G Protein-Coupled Receptor 75 (GPR75) (AA 1-540) protein (Strep Tag)Crystallography grade GPR75 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
G Protein-Coupled Receptor 75 (GPR75) (AA 1-540) protein (Strep Tag)Crystallography grade GPR75 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
G Protein-Coupled Receptor 75 (GPR75) (AA 372-540) protein (His-SUMO Tag)GPR75 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
G Protein-Coupled Receptor 75 (GPR75) (AA 372-540) protein (His tag)GPR75 Origin: Human Host: Yeast Recombinant > 90 % SDS
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- Application Notes
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- Applications for VLPs:
- ELISA
- SPR affinity analysis
- Phage display screening
- Immunization
- Cell based assays
- CAR-T cell screening
- Protein cystal structure analysis
- Comment
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Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- GPR75 (G Protein-Coupled Receptor 75 (GPR75))
- Alternative Name
- GPR75 (GPR75 Products)
- Synonyms
- GPR75 Protein, GPRchr2 Protein, WI31133 Protein, G protein-coupled receptor 75 Protein, G protein-coupled receptor 75 S homeolog Protein, GPR75 Protein, gpr75 Protein, Gpr75 Protein, gpr75.S Protein
- Background
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GPRchr2,
Description: WI31133G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor. - Molecular Weight
- The human full length GPR75 protein has a MW of 59.4 kDa
- UniProt
- O95800
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