KCNK9 Protein
KCNK9
Origin: Human
Host: HEK-293 Cells
Synthetic
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- Target See all KCNK9 Proteins
- KCNK9 (Potassium Channel, Subfamily K, Member 9 (KCNK9))
- Protein Type
- Synthetic
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Origin
- Human
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Source
- HEK-293 Cells
- Purpose
- Human KCNK9 full length protein-synthetic nanodisc
- Characteristics
- Full Length Transmembrane Proteins (synthetic Nanodisc)
- Top Product
- Discover our top product KCNK9 Protein
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- Application Notes
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- Applications for VLPs:
- ELISA
- SPR affinity analysis
- Phage display screening
- Immunization
- Cell based assays
- CAR-T cell screening
- Protein cystal structure analysis
- Comment
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Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- KCNK9 (Potassium Channel, Subfamily K, Member 9 (KCNK9))
- Alternative Name
- KCNK9 (KCNK9 Products)
- Synonyms
- Task3 Protein, K2p9.1 Protein, KT3.2 Protein, TASK-3 Protein, TASK3 Protein, KCNK9 Protein, LOC799704 Protein, Kcnk9 Protein, task3 Protein, k2p9.1 Protein, task-3 Protein, kt3.2 Protein, potassium channel, subfamily K, member 9 Protein, potassium two pore domain channel subfamily K member 9 Protein, potassium channel, two pore domain subfamily K, member 9 Protein, potassium channel, two pore domain subfamily K, member 9 L homeolog Protein, Kcnk9 Protein, KCNK9 Protein, kcnk9 Protein, kcnk9.L Protein
- Background
- This gene encodes a protein that contains multiple transmembrane regions and two pore-forming P domains and functions as a pH -dependent potassium channel. Amplification and overexpression of this gene have been observed in several types of human carcinomas. This gene is imprinted in the brain, with preferential expression from the maternal allele. A mutation in this gene was associated with Birk-Barel dysmorphism syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2017]
- Molecular Weight
- The human full length KCNK9 protein has a MW of 42.3 kDa
- UniProt
- Q9NPC2
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