Claudin 5 Protein (CLDN5)
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- Target See all Claudin 5 (CLDN5) Proteins
- Claudin 5 (CLDN5)
- Protein Type
- Synthetic
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Origin
- Human
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Source
- HEK-293 Cells
- Purpose
- Human CLDN5 full length protein-synthetic nanodisc
- Characteristics
- Full Length Transmembrane Proteins (synthetic Nanodisc)
- Top Product
- Discover our top product CLDN5 Protein
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Claudin 5 (CLDN5) (AA 145-218) protein (His-IF2DI Tag)
CLDN5 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Claudin 5 (CLDN5) (AA 29-81) protein (GST tag)CLDN5 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Claudin 5 (CLDN5) (AA 1-218) protein (GST tag)CLDN5 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Claudin 5 (CLDN5) (AA 1-218) protein (Strep Tag)Crystallography grade CLDN5 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Claudin 5 (CLDN5) (AA 1-218) protein (Strep Tag)Crystallography grade CLDN5 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
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- Application Notes
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- Applications for VLPs:
- ELISA
- SPR affinity analysis
- Phage display screening
- Immunization
- Cell based assays
- CAR-T cell screening
- Protein cystal structure analysis
- Comment
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Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- Claudin 5 (CLDN5)
- Alternative Name
- CLDN5 (CLDN5 Products)
- Synonyms
- AWAL Protein, BEC1 Protein, CPETRL1 Protein, TMVCF Protein, cld5 Protein, awal Protein, bec1 Protein, claudin-5 Protein, cpetrl1 Protein, tmvcf Protein, AI854493 Protein, MBEC1 Protein, Tmvcf Protein, cldn5 Protein, zgc:85723 Protein, zgc:103419 Protein, claudin 5 Protein, Claudin-5 Protein, claudin 5 (transmembrane protein deleted in velocardiofacial syndrome) Protein, claudin 5a Protein, claudin 5b Protein, claudin 5 (transmembrane protein deleted in velocardiofacial syndrome) L homeolog Protein, CLDN5 Protein, cld5 Protein, cldn5 Protein, Cldn5 Protein, cldn5a Protein, cldn5b Protein, cldn5.L Protein
- Background
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AWAL, BEC1, CPETRL1, TMDVCF, TMVCF
Description: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2018] - Molecular Weight
- The human full length CLDN5 protein has a MW of 31.4 kDa
- UniProt
- O00501
- Pathways
- Hepatitis C
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