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Claudin 9 Protein (CLDN9)

CLDN9 Origin: Human Host: HEK-293 Cells Synthetic
Catalog No. ABIN7491609
  • Target See all Claudin 9 (CLDN9) Proteins
    Claudin 9 (CLDN9)
    Protein Type
    Synthetic
    Origin
    • 5
    • 1
    Human
    Source
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purpose
    Human CLDN9 full length protein-synthetic nanodisc
    Characteristics
    Full Length Transmembrane Proteins (synthetic Nanodisc)
    Top Product
    Discover our top product CLDN9 Protein
  • Application Notes
    • Applications for VLPs:
    • ELISA
    • SPR affinity analysis
    • Phage display screening
    • Immunization
    • Cell based assays
    • CAR-T cell screening
    • Protein cystal structure analysis
    Comment

    Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    Claudin 9 (CLDN9)
    Alternative Name
    CLDN9 (CLDN9 Products)
    Synonyms
    CLDN9 Protein, nmf329 Protein, claudin 9 Protein, CLDN9 Protein, Cldn9 Protein
    Background
    DFNB116
    Description: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This protein is one of the entry cofactors for hepatitis C virus. Mouse studies revealed that this gene is required for the preservation of sensory cells in the hearing organ and the gene deficiency is associated with deafness. [provided by RefSeq, Jun 2010]
    Molecular Weight
    The human full length CLDN9 protein has a MW of 22.8 kDa
    UniProt
    O95484
    Pathways
    Cell-Cell Junction Organization, Hepatitis C
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