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Claudin 2 Protein (CLDN2)

CLDN2 Origin: Human Host: HEK-293 Cells Synthetic
Catalog No. ABIN7491596
  • Target See all Claudin 2 (CLDN2) Proteins
    Claudin 2 (CLDN2)
    Protein Type
    Synthetic
    Origin
    • 6
    • 3
    Human
    Source
    • 3
    • 2
    • 2
    • 2
    HEK-293 Cells
    Purpose
    Human CLDN2 full length protein-synthetic nanodisc
    Characteristics
    Full Length Transmembrane Proteins (synthetic Nanodisc)
    Top Product
    Discover our top product CLDN2 Protein
  • Application Notes
    • Applications for VLPs:
    • ELISA
    • SPR affinity analysis
    • Phage display screening
    • Immunization
    • Cell based assays
    • CAR-T cell screening
    • Protein cystal structure analysis
    Comment

    Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    Claudin 2 (CLDN2)
    Alternative Name
    CLDN2 (CLDN2 Products)
    Synonyms
    CLDN2 Protein, zgc:92260 Protein, AL022813 Protein, RGD1560247 Protein, claudin 2 Protein, CLDN2 Protein, cldn2 Protein, Cldn2 Protein
    Background
    OAZON
    Description: This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.[provided by RefSeq, Jan 2010]
    Molecular Weight
    The human full length CLDN2 protein has a MW of 25 kDa
    UniProt
    P57739
    Pathways
    Hepatitis C
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