GLUT12 Protein

Catalog No. ABIN7491731

Product Details

Target: GLUT12 (SLC2A12) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 12 (SLC2A12))

Protein Type: Synthetic

Origin: Human

Source: HEK-293 Cells

Purpose: Human SLC2A12 full length protein-synthetic nanodisc

Characteristics: Full Length Transmembrane Proteins (synthetic Nanodisc)

Application Details

Application Notes:

• Applications for VLPs:
• ELISA
• SPR affinity analysis
• Phage display screening
• Immunization
• Cell based assays
• CAR-T cell screening
• Protein cystal structure analysis

Comment:

Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: GLUT12 (SLC2A12) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 12 (SLC2A12))

Alternative Name: SLC2A12 (SLC2A12 Products)

Synonyms: zgc:66027 Protein, zgc:85776 Protein, SLC2A12 Protein, GLUT12 Protein, GLUT8 Protein, GLUT-12 Protein, Glut12 Protein, glut12 Protein, solute carrier family 2 (facilitated glucose transporter), member 12 Protein, solute carrier family 2 member 12 Protein, solute carrier family 2 (facilitated glucose transporter), member 12 L homeolog Protein, slc2a12 Protein, SLC2A12 Protein, Slc2a12 Protein, slc2a12.L Protein

Background: GLUT12, GLUT8
Description: SLC2A12 belongs to a family of transporters that catalyze the uptake of sugars through facilitated diffusion (Rogers et al., 2002). This family of transporters show conservation of 12 transmembrane helices as well as functionally significant amino acid residues (Joost and Thorens, 2001 [PubMed 11780753]).[supplied by OMIM, Mar 2008]

Molecular Weight: The human full length SLC2A12 protein has a MW of 67 kDa

UniProt: Q8TD20

Pathways: Warburg Effect