CXCR1 Protein
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- Target See all CXCR1 Proteins
- CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))
- Protein Type
- Synthetic
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Origin
- Human
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Source
- HEK-293 Cells
- Purpose
- Human CXCR1 full length protein-synthetic nanodisc
- Characteristics
- Full Length Transmembrane Proteins (synthetic Nanodisc)
- Top Product
- Discover our top product CXCR1 Protein
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Chemokine (C-X-C Motif) Receptor 1 (CXCR1) (AA 1-350) protein (GST tag)
CXCR1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Chemokine (C-X-C Motif) Receptor 1 (CXCR1) (AA 1-350) protein (Strep Tag)Crystallography grade CXCR1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Chemokine (C-X-C Motif) Receptor 1 (CXCR1) (AA 1-351) protein (Strep Tag)Crystallography grade CXCR1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
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- Application Notes
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- Applications for VLPs:
- ELISA
- SPR affinity analysis
- Phage display screening
- Immunization
- Cell based assays
- CAR-T cell screening
- Protein cystal structure analysis
- Comment
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Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))
- Alternative Name
- CXCR1 (CXCR1 Products)
- Synonyms
- C-C Protein, C-C-CKR-1 Protein, CD128 Protein, CD181 Protein, CDw128a Protein, CKR-1 Protein, CMKAR1 Protein, IL8R1 Protein, IL8RA Protein, IL8RBA Protein, Il8ra Protein, CXCR-1 Protein, IL-8RA Protein, CXCR2 Protein, IL8RB Protein, cxcr1 Protein, cxcr2 Protein, C-X-C motif chemokine receptor 1 Protein, chemokine (C-X-C motif) receptor 1 Protein, C-X-C chemokine receptor type 1 Protein, C-X-C motif chemokine receptor 1 S homeolog Protein, CXCR1 Protein, Cxcr1 Protein, LOC100461947 Protein, cxcr1.S Protein
- Background
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C-C, C-C-CKR-1, CD128, CD181, CDw128a, CKR-1, CMKAR1, IL8R1, IL8RA, IL8RBA
Description: The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. [provided by RefSeq, Jul 2008] - Molecular Weight
- The human full length CXCR1 protein has a MW of 39.8 kDa
- UniProt
- P25024
- Pathways
- cAMP Metabolic Process
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