Prokineticin Receptor 1 Protein (PROKR1)
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- Target See all Prokineticin Receptor 1 (PROKR1) Proteins
- Prokineticin Receptor 1 (PROKR1)
- Protein Type
- Synthetic
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Origin
- Human
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Source
- HEK-293 Cells
- Purpose
- Human PROKR1 full length protein-synthetic nanodisc
- Characteristics
- Full Length Transmembrane Proteins (synthetic Nanodisc)
- Top Product
- Discover our top product PROKR1 Protein
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Prokineticin Receptor 1 (PROKR1) (AA 1-393) protein (Strep Tag)
Crystallography grade PROKR1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Prokineticin Receptor 1 (PROKR1) (AA 1-393) protein (Strep Tag)Crystallography grade PROKR1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Prokineticin Receptor 1 (PROKR1) protein (Myc-DYKDDDDK Tag)PROKR1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
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- Applications for VLPs:
- ELISA
- SPR affinity analysis
- Phage display screening
- Immunization
- Cell based assays
- CAR-T cell screening
- Protein cystal structure analysis
- Comment
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Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- Prokineticin Receptor 1 (PROKR1)
- Alternative Name
- PROKR1 (PROKR1 Products)
- Synonyms
- EG-VEGFR1 Protein, Gpr73 Protein, Pkr1 Protein, GPR73 Protein, GPR73a Protein, PKR1 Protein, ZAQ Protein, PROKR1 Protein, prokineticin receptor 1 Protein, Prokr1 Protein, PROKR1 Protein
- Background
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GPR73, GPR73a, PK-R1, PKR1, ZAQ
Description: This gene encodes a member of the G-protein-coupled receptor family. The encoded protein binds to prokineticins (1 and 2), leading to the activation of MAPK and STAT signaling pathways. Prokineticins are protein ligands involved in angiogenesis and inflammation. The encoded protein is expressed in peripheral tissues such as those comprising the circulatory system, lungs, reproductive system, endocrine system and the gastrointestinal system. The protein may be involved in signaling in human fetal ovary during initiation of primordial follicle formation. Sequence variants in this gene may be associated with recurrent miscarriage. [provided by RefSeq, Aug 2016] - Molecular Weight
- The human full length PROKR1 protein has a MW of 44.6 kDa
- UniProt
- Q8TCW9
- Pathways
- Hedgehog Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
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