GPR65 Protein
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- Target See all GPR65 Proteins
- GPR65 (G Protein-Coupled Receptor 65 (GPR65))
- Protein Type
- Synthetic
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Origin
- Human
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Source
- HEK-293 Cells
- Purpose
- Human GPR65 full length protein-synthetic nanodisc
- Characteristics
- Full Length Transmembrane Proteins (synthetic Nanodisc)
- Top Product
- Discover our top product GPR65 Protein
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G Protein-Coupled Receptor 65 (GPR65) (AA 1-337) protein (GST tag)
GPR65 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
G Protein-Coupled Receptor 65 (GPR65) (AA 1-337) protein (Strep Tag)Crystallography grade GPR65 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
G Protein-Coupled Receptor 65 (GPR65) (AA 1-337) protein (Strep Tag)Crystallography grade GPR65 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- Application Notes
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- Applications for VLPs:
- ELISA
- SPR affinity analysis
- Phage display screening
- Immunization
- Cell based assays
- CAR-T cell screening
- Protein cystal structure analysis
- Comment
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Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- GPR65 (G Protein-Coupled Receptor 65 (GPR65))
- Alternative Name
- GPR65 (GPR65 Products)
- Synonyms
- tdag8 Protein, htdag8 Protein, TDAG8 Protein, hTDAG8 Protein, Dig1 Protein, Gpcr25 Protein, Tdag8 Protein, G protein-coupled receptor 65 Protein, G-protein coupled receptor 65 Protein, GPR65 Protein, gpr65 Protein, Gpr65 Protein
- Background
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HTDAG8, TDAG8
Description: Receptor for the glycosphingolipid psychosine (PSY) and several related glycosphingolipids (PubMed:11309421). Plays a role in immune response by maintaining lysosome function and supporting phagocytosis-mediated intracellular bacteria clearance (PubMed:27287411). May have a role in activation-induced cell death or differentiation of T-cells (By similarity).[UniProtKB/Swiss-Prot Function] - Molecular Weight
- The human full length GPR65 protein has a MW of 39.3 kDa
- UniProt
- Q8IYL9
- Pathways
- cAMP Metabolic Process
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