XCR1 Protein
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- Target See all XCR1 Proteins
- XCR1 (Chemokine (C Motif) Receptor 1 (XCR1))
- Protein Type
- Synthetic
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Origin
- Human
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Source
- HEK-293 Cells
- Purpose
- Human XCR1 full length protein-synthetic nanodisc
- Characteristics
- Full Length Transmembrane Proteins (synthetic Nanodisc)
- Top Product
- Discover our top product XCR1 Protein
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Chemokine (C Motif) Receptor 1 (XCR1) (AA 1-333) protein (Strep Tag)
Crystallography grade XCR1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
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- Application Notes
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- Applications for VLPs:
- ELISA
- SPR affinity analysis
- Phage display screening
- Immunization
- Cell based assays
- CAR-T cell screening
- Protein cystal structure analysis
- Comment
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Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- XCR1 (Chemokine (C Motif) Receptor 1 (XCR1))
- Alternative Name
- XCR1 (XCR1 Products)
- Synonyms
- CCXCR1-L Protein, XCR1 Protein, CCXCR1 Protein, GPR5 Protein, Ccxcr1 Protein, Gpr5 Protein, mXcr1 Protein, X-C motif chemokine receptor 1 Protein, chemokine (C motif) receptor 1a, duplicate 1 Protein, chemokine (C motif) receptor 1 Protein, XCR1 Protein, xcr1a.1 Protein, Xcr1 Protein
- Background
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CCXCR1, GPR5
Description: The protein encoded by this gene is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids. This receptor is most closely related to RBS11 and the MIP1-alpha/RANTES receptor. It transduces a signal by increasing the intracellular calcium ions level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Several alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Apr 2020] - Molecular Weight
- The human full length XCR1 protein has a MW of 38.3 kDa
- UniProt
- P46094
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