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BDKRB2 Protein

BDKRB2 Origin: Human Host: HEK-293 Cells Synthetic
Catalog No. ABIN7491547
  • Target See all BDKRB2 Proteins
    BDKRB2 (Bradykinin Receptor B2 (BDKRB2))
    Protein Type
    Synthetic
    Origin
    • 4
    • 2
    • 1
    • 1
    Human
    Source
    • 3
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purpose
    Human BDKRB2 full length protein-synthetic nanodisc
    Characteristics
    Full Length Transmembrane Proteins (synthetic Nanodisc)
    Top Product
    Discover our top product BDKRB2 Protein
  • Application Notes
    • Applications for VLPs:
    • ELISA
    • SPR affinity analysis
    • Phage display screening
    • Immunization
    • Cell based assays
    • CAR-T cell screening
    • Protein cystal structure analysis
    Comment

    Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    BDKRB2 (Bradykinin Receptor B2 (BDKRB2))
    Alternative Name
    BDKRB2 (BDKRB2 Products)
    Synonyms
    BDKRB2 Protein, b2r Protein, bk2 Protein, bk-2 Protein, bkr2 Protein, brb2 Protein, kinrec Protein, B2R Protein, BK-2 Protein, BK2 Protein, BKR2 Protein, BRB2 Protein, B2BKR Protein, B2BRA Protein, B(2) Protein, B2 Protein, BK2R Protein, Bdkrb2 Protein, bradykinin receptor B2 Protein, bradykinin receptor, beta 2 Protein, bradykinin type 2 receptor Protein, Bdkrb2 Protein, BDKRB2 Protein, bdkrb2 Protein, kinrec Protein, B2R Protein
    Background
    B2R, BK-2, BK2, BKR2, BRB2
    Description: This gene encodes a receptor for bradykinin. The 9 aa bradykinin peptide elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. Bradykinin is released upon activation by pathophysiologic conditions such as trauma and inflammation, and binds to its kinin receptors, B1 and B2. The B2 receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. [provided by RefSeq, Apr 2020]
    Molecular Weight
    The human full length BDKRB2 protein has a MW of 44.5 kDa
    UniProt
    P30411
    Pathways
    ACE Inhibitor Pathway, Negative Regulation of intrinsic apoptotic Signaling
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