CMKLR1 Protein
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- Target See all CMKLR1 Proteins
- CMKLR1 (Chemokine-Like Receptor 1 (CMKLR1))
- Protein Type
- Synthetic
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Origin
- Human
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Source
- HEK-293 Cells
- Purpose
- Human CMKLR1 full length protein-synthetic nanodisc
- Characteristics
- Full Length Transmembrane Proteins (synthetic Nanodisc)
- Top Product
- Discover our top product CMKLR1 Protein
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Chemokine-Like Receptor 1 (CMKLR1) (AA 1-371) protein (GST tag)
CMKLR1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Chemokine-Like Receptor 1 (CMKLR1) (AA 1-373) protein (Strep Tag)Crystallography grade CMKLR1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Chemokine-Like Receptor 1 (CMKLR1) (AA 1-371) protein (Strep Tag)Crystallography grade CMKLR1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- Application Notes
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- Applications for VLPs:
- ELISA
- SPR affinity analysis
- Phage display screening
- Immunization
- Cell based assays
- CAR-T cell screening
- Protein cystal structure analysis
- Comment
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Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- CMKLR1 (Chemokine-Like Receptor 1 (CMKLR1))
- Alternative Name
- CMKLR1 (CMKLR1 Products)
- Synonyms
- CHEMERINR Protein, ChemR23 Protein, DEZ Protein, RVER1 Protein, Gpcr27 Protein, mcmklr1 Protein, si:ch211-240b21.3 Protein, CMLKR1 Protein, Cmklr-1 Protein, GPCR Protein, chemerin chemokine-like receptor 1 Protein, chemokine-like receptor 1 Protein, CMKLR1 Protein, Cmklr1 Protein, cmklr1 Protein
- Background
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CHEMERINR, ChemR23, DEZ, RVER1
Description: Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. Positively regulates adipogenesis and adipocyte metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2).[UniProtKB/Swiss-Prot Function] - Molecular Weight
- The human full length CMKLR1 protein has a MW of 42.1 kDa
- UniProt
- Q99788
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