HRH3 Protein
HRH3
Origin: Human
Host: HEK-293 Cells
Synthetic
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- Target See all HRH3 Proteins
- HRH3 (Histamine Receptor H3 (HRH3))
- Protein Type
- Synthetic
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Origin
- Human
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Source
- HEK-293 Cells
- Purpose
- Human HRH3 full length protein-synthetic nanodisc
- Characteristics
- Full Length Transmembrane Proteins (synthetic Nanodisc)
- Top Product
- Discover our top product HRH3 Protein
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Histamine Receptor H3 (HRH3) (AA 257-359) protein (GST tag)
HRH3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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- Application Notes
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- Applications for VLPs:
- ELISA
- SPR affinity analysis
- Phage display screening
- Immunization
- Cell based assays
- CAR-T cell screening
- Protein cystal structure analysis
- Comment
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Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)
- Storage
- RT,-20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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- Target
- HRH3 (Histamine Receptor H3 (HRH3))
- Alternative Name
- HRH3 (HRH3 Products)
- Synonyms
- GPCR97 Protein, HH3R Protein, AW049250 Protein, H3R Protein, histamine receptor H3 Protein, HRH3 Protein, Hrh3 Protein
- Background
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GPCR97, HH3R
Description: Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and can regulate neurotransmitter release. This receptor can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system. [provided by RefSeq, Jul 2008] - Molecular Weight
- The human full length HRH3 protein has a MW of 48.5 kDa
- UniProt
- Q9Y5N1
- Pathways
- cAMP Metabolic Process, Feeding Behaviour
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