LILRA4 Protein (His tag)
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- Target See all LILRA4 Proteins
- LILRA4 (Leukocyte Immunoglobulin-Like Receptor, Subfamily A (With TM Domain), Member 4 (LILRA4))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This LILRA4 protein is labelled with His tag.
- Purpose
- Human LILRA4 / CD85g / ILT7 Protein, His Tag
- Sequence
- Glu 24 - Asn 446
- Characteristics
- Human LILRA4 Protein, His Tag is expressed from human 293 cells (HEK293). It contains AA Glu 24 - Asn 446 (Accession # P59901-1).
- Purity
- 90 %
- Endotoxin Level
- 1.0 EU per μg
- Top Product
- Discover our top product LILRA4 Protein
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Leukocyte Immunoglobulin-Like Receptor, Subfamily A (With TM Domain), Member 4 (LILRA4) protein (His tag)
LILRA4 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Leukocyte Immunoglobulin-Like Receptor, Subfamily A (With TM Domain), Member 4 (LILRA4) (AA 24-446) protein (His-Avi Tag)LILRA4 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Leukocyte Immunoglobulin-Like Receptor, Subfamily A (With TM Domain), Member 4 (LILRA4) (AA 24-446) protein (His-Avi Tag,Biotin)LILRA4 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Leukocyte Immunoglobulin-Like Receptor, Subfamily A (With TM Domain), Member 4 (LILRA4) (AA 1-499) protein (GST tag)LILRA4 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Leukocyte Immunoglobulin-Like Receptor, Subfamily A (With TM Domain), Member 4 (LILRA4) (AA 24-446) protein (His tag)Crystallography grade LILRA4 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
Leukocyte Immunoglobulin-Like Receptor, Subfamily A (With TM Domain), Member 4 (LILRA4) (AA 24-499) protein (rho-1D4 tag)Crystallography grade LILRA4 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
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- Comment
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This protein carries a polyhistidine tag at the C-terminus. (10xHis) The protein has a calculated MW of 48.5 kDa. The protein migrates as 60-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -20 °C
- Storage Comment
- -20°C
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- Target
- LILRA4 (Leukocyte Immunoglobulin-Like Receptor, Subfamily A (With TM Domain), Member 4 (LILRA4))
- Alternative Name
- LILRA4 (LILRA4 Products)
- Synonyms
- ILT7 Protein, CD85g Protein, leukocyte immunoglobulin like receptor A4 Protein, LILRA4 Protein
- Background
- Leukocyte immunoglobulin-like receptor subfamily A member 4 (LILRA4/ILT7/CD85g) is a marker of plasmacytoid dendritic cells (pDCs), which are reported to be a major source of the abnormally high levels of IFNα associated with autoimmune diseases. Targeting LILRA4 with therapeutic antibodies to promote killing of these IFNα-producing pDCs is being investigated as a novel approach to alleviating the symptoms of autoimmune diseases. LILRA4 is an immunoglobulin-like protein preferentially expressed on the surface of human plasmacytoid dendritic cells (pDCs). It interacts with bone marrow stromal cell antigen 2 to control the Toll-like receptor (TLR) driven response by pDCs to viral infection. It may also be involved in modulating pDC-tumour interactions. pDCs are a source of the excess IFNα which drives autoimmune disease symptoms.
- Molecular Weight
- 48.5 kDa
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