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LRP1 Protein (Fc Tag)

MALS verified LRP1 Origin: Human Host: HEK-293 Cells Recombinant 95 %
Catalog No. ABIN7482511
  • Target See all LRP1 Proteins
    LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))
    Protein Type
    Recombinant
    Origin
    • 4
    • 3
    Human
    Source
    • 5
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This LRP1 protein is labelled with Fc Tag.
    Purpose
    Human LRP-1 / cluster II Protein, Fc Tag (MALS verified)
    Sequence
    Arg 786 - Leu 1165
    Characteristics
    Human cluster II Protein, Fc Tag is expressed from human 293 cells (HEK293). It contains AA Arg 786 - Leu 1165 (Accession # Q07954-1).
    Purity
    95 %
    Endotoxin Level
    0.1 EU per μg
    Grade
    MALS verified
    Top Product
    Discover our top product LRP1 Protein
  • Comment

    This protein carries a human IgG1 Fc tag at the C-terminus. (Fc) The protein has a calculated MW of 68.0kDa. The protein migrates as 75-105 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Storage
    -20 °C
    Storage Comment
    -20°C
  • Target
    LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))
    Alternative Name
    LRP-1 (LRP1 Products)
    Synonyms
    A2MR Protein, APOER Protein, APR Protein, CD91 Protein, IGFBP3R Protein, LRP Protein, LRP1A Protein, TGFBR5 Protein, A2mr Protein, AI316852 Protein, Lrp Protein, LRP-1 Protein, LDL receptor related protein 1 Protein, prolow-density lipoprotein receptor-related protein 1 Protein, low density lipoprotein receptor-related protein 1 Protein, LRP1 Protein, Lrp1 Protein, LOC100414789 Protein
    Background
    Low density lipoprotein receptor-related protein 1 (LRP1), also known as alpha-2-macroglobulin receptor (A2MR), apolipoprotein E receptor (APOER) or cluster of differentiation 91 (CD91), is a protein forming a receptor found in the plasma membrane of cells. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor. LRP1 is also a key signalling protein and, thus, involved in various biological processes, such as lipoprotein metabolism and cell motility, and diseases, such as neurodegenerative diseases, atherosclerosis, and cancer.
    Molecular Weight
    68.0kDa
    Pathways
    Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
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