LRP1 Protein (Fc Tag)
-
- Target See all LRP1 Proteins
- LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This LRP1 protein is labelled with Fc Tag.
- Purpose
- Human LRP-1 / cluster II Protein, Fc Tag (MALS verified)
- Sequence
- Arg 786 - Leu 1165
- Characteristics
- Human cluster II Protein, Fc Tag is expressed from human 293 cells (HEK293). It contains AA Arg 786 - Leu 1165 (Accession # Q07954-1).
- Purity
- 95 %
- Endotoxin Level
- 0.1 EU per μg
- Grade
- MALS verified
- Top Product
- Discover our top product LRP1 Protein
-
-
- Comment
-
This protein carries a human IgG1 Fc tag at the C-terminus. (Fc) The protein has a calculated MW of 68.0kDa. The protein migrates as 75-105 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -20 °C
- Storage Comment
- -20°C
-
- Target
- LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))
- Alternative Name
- LRP-1 (LRP1 Products)
- Synonyms
- A2MR Protein, APOER Protein, APR Protein, CD91 Protein, IGFBP3R Protein, LRP Protein, LRP1A Protein, TGFBR5 Protein, A2mr Protein, AI316852 Protein, Lrp Protein, LRP-1 Protein, LDL receptor related protein 1 Protein, prolow-density lipoprotein receptor-related protein 1 Protein, low density lipoprotein receptor-related protein 1 Protein, LRP1 Protein, Lrp1 Protein, LOC100414789 Protein
- Background
- Low density lipoprotein receptor-related protein 1 (LRP1), also known as alpha-2-macroglobulin receptor (A2MR), apolipoprotein E receptor (APOER) or cluster of differentiation 91 (CD91), is a protein forming a receptor found in the plasma membrane of cells. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor. LRP1 is also a key signalling protein and, thus, involved in various biological processes, such as lipoprotein metabolism and cell motility, and diseases, such as neurodegenerative diseases, atherosclerosis, and cancer.
- Molecular Weight
- 68.0kDa
- Pathways
- Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
-