MICA Protein (AA 24-309) (mFc Tag)
Quick Overview for MICA Protein (AA 24-309) (mFc Tag) (ABIN7489076)
Target
See all MICA ProteinsProtein Type
Origin
Source
Purity
Grade
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Protein Characteristics
- AA 24-309
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Purification tag / Conjugate
- This MICA protein is labelled with mFc Tag.
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Purpose
- Human MICA (24-202) Protein, Mouse IgG2a Fc Tag (MALS verified)
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Sequence
- Glu 24 - Arg 202
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Characteristics
- Human MICA (24-202) Protein, Mouse IgG2a Fc Tag is expressed from human 293 cells (HEK293). It contains AA Glu 24 - Arg 202 (Accession # Q29983-1).
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Endotoxin Level
- 1.0 EU per μg
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MHC Class I Polypeptide-Related Sequence A (MICA) (AA 24-308) (Active) protein (Biotin,His-Avi Tag)
MICA Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
MHC Class I Polypeptide-Related Sequence A (MICA) (AA 1-284) (Active) protein (His tag)MICA Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
MHC Class I Polypeptide-Related Sequence A (MICA) (AA 24-308) (Active) protein (His-Avi Tag)MICA Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
MHC Class I Polypeptide-Related Sequence A (MICA) (AA 24-307) protein (His tag)MICA Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
MHC Class I Polypeptide-Related Sequence A (MICA) (AA 24-308) (Active) protein (Fc Tag)MICA Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
MHC Class I Polypeptide-Related Sequence A (MICA) (AA 1-383) protein (GST tag)MICA Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
MHC Class I Polypeptide-Related Sequence A (MICA) (AA 24-307) protein (His tag)MICA Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
MHC Class I Polypeptide-Related Sequence A (MICA) (AA 24-306) protein (His-IF2DI Tag)MICA Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
MHC Class I Polypeptide-Related Sequence A (MICA) (AA 24-297) (Active) protein (His tag)MICA Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS, AcA Active
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Comment
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This protein carries a mouse IgG2a Fc tag at the C-terminus. (mFc(mIgG2a) The protein has a calculated MW of 47.8 kDa. The protein migrates as 57-64 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Storage
- -20 °C
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Storage Comment
- -20°C
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- MICA (MHC Class I Polypeptide-Related Sequence A (MICA))
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Alternative Name
- MICA
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Background
- MHC class I polypeptide-related sequence A (MICA) belongs to the MHC class I family and MIC subfamily. MICA contains one Ig-like C1-type (immunoglobulin-like) domain. Unlike classical MHC class I molecules, MICA does not form a heterodimer with beta-2-microglobulin. MICA acts as a stress-induced self-antigen that is recognized by gamma delta T-cells. MICA is ligand for the KLRK1/NKG2D receptor. MICA bind to KLRK1 leads to cell lysis.
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Molecular Weight
- 47.8 kDa
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Pathways
- Activation of Innate immune Response, Transition Metal Ion Homeostasis, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
Target
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