MAPT Protein

Catalog No. ABIN7488816

This Recombinant MAPT protein is expressed in Escherichia coli (E. coli).

Quick Overview for MAPT Protein (ABIN7488816)

Target: MAPT (Microtubule-Associated Protein tau (MAPT))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Escherichia coli (E. coli)

Purity: 95 %

Product Details

Purpose: Human Tau-441 / 2N4R Pre-formed Fibrils Protein, Tag Free (ThT active)

Sequence: Met 1 - Leu 441

Characteristics: Human Tau-441 Pre-formed Fibrils, Tag Free is expressed from E.coli cells. It contains AA Met 1 - Leu 441 (Accession # P10636-8).

Endotoxin Level: 0.05 EU per μg

Application Details

Comment:

This protein carries no "tag". () The protein has a calculated MW of 45.8 kDa.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 50 mM Tris, 150 mM NaCl, 1 mM DTT, 1 mM EDTA, pH 7.5

Storage: -80 °C

Storage Comment: -70°C

Target Details

Target: MAPT (Microtubule-Associated Protein tau (MAPT))

Alternative Name: Tau-441

Background: Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease, frontotemporal dementia, and other tauopathies.

Molecular Weight: 45.8 kDa

NCBI Accession: NP_005901

Pathways: MAPK Signaling, Microtubule Dynamics, M Phase, Regulation of Cell Size