C-Type Lectin Domain Family 4, Member M (CLEC4M) (AA 71-399) Protein
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- Target See all C-Type Lectin Domain Family 4, Member M (CLEC4M) Proteins
- C-Type Lectin Domain Family 4, Member M (CLEC4M)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 71-399
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Origin
- Human
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Source
- HEK-293 Cells
- Purpose
- Human CLEC4M/CD299 Protein
- Sequence
- Gln71-Glu399
- Characteristics
- Recombinant Human CLEC4M/CD299 Protein is expressed from HEK293 without tag.It contains Gln71-Glu399.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product CLEC4M Protein
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C-Type Lectin Domain Family 4, Member M (CLEC4M) (AA 285-394) protein (GST tag)
CLEC4M Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
C-Type Lectin Domain Family 4, Member M (CLEC4M) (AA 71-399) protein (His tag)Crystallography grade CLEC4M Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
C-Type Lectin Domain Family 4, Member M (CLEC4M) (AA 1-399) protein (Strep Tag)Crystallography grade CLEC4M Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
C-Type Lectin Domain Family 4, Member M (CLEC4M) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)CLEC4M Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
C-Type Lectin Domain Family 4, Member M (CLEC4M) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)CLEC4M Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- C-Type Lectin Domain Family 4, Member M (CLEC4M)
- Alternative Name
- CLEC4M (CLEC4M Products)
- Synonyms
- CD209L Protein, CD299 Protein, DC-SIGN2 Protein, DC-SIGNR Protein, DCSIGNR Protein, HP10347 Protein, L-SIGN Protein, LSIGN Protein, CD209B Protein, C-type lectin domain family 4 member M Protein, CLEC4M Protein
- Background
- CLEC4M, also known as DC-SIGNR, L-SIGN or CD209L, is a Ca2+-dependent C-type lectin. CLEC4M and its homologue DC-SIGN are encoded by the closely related lectin gene cluster on chromosome 19p13.3. higher expression of CLEC4M is associated with poor clinical prognosis in lung cancer patients and enhances the resistance of NSCLC cells to cisplatin. Inhibition of CLEC4M expression significantly increased cisplatin sensitivity, suggesting potential clinical significance for targeting CLEC4M in overcoming cisplatin resistance.
- Molecular Weight
- 37.72 kDa. Due to glycosylation, the protein migrates to 38-50 kDa based on Tris-Bis PAGE result.
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