FCN1 Protein (AA 30-326) (His tag)
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- Target See all FCN1 Proteins
- FCN1 (Ficolin (Collagen/fibrinogen Domain Containing) 1 (FCN1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 30-326
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This FCN1 protein is labelled with His tag.
- Purpose
- Human ficolin 1/FCN1 Protein
- Sequence
- Ala30-Ala326
- Characteristics
- Recombinant Human ficolin 1/FCN1 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Ala30-Ala326.
- Purity
- > 95 % as determined by Tris-Bis PAGE
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product FCN1 Protein
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Ficolin (Collagen/fibrinogen Domain Containing) 1 (FCN1) (AA 1-326) protein (GST tag)
FCN1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Ficolin (Collagen/fibrinogen Domain Containing) 1 (FCN1) (AA 201-300) protein (GST tag)FCN1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Ficolin (Collagen/fibrinogen Domain Containing) 1 (FCN1) (AA 18-334) protein (His tag)Crystallography grade FCN1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Ficolin (Collagen/fibrinogen Domain Containing) 1 (FCN1) proteinFCN1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22 μm filtered solution in PBS, 350 mM NaCl, 200 mM Arginine ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- FCN1 (Ficolin (Collagen/fibrinogen Domain Containing) 1 (FCN1))
- Alternative Name
- ficolin 1 (FCN1 Products)
- Synonyms
- FCNM Protein, FCNB Protein, FCN2 Protein, FCN1 Protein, ficolin 1 Protein, ficolin (collagen/fibrinogen domain containing) 1 Protein, ficolin-1 Protein, FCN1 Protein, Fcn1 Protein, LOC100069029 Protein
- Background
- The ficolins are members of a recently discovered family of host innate opsonins that can activate the lectin pathway of complement. The ficolins bind many ligands, although they are typically described as binding acetylated sugars. Ficolin-1 is the least-described of the Ficolins and is expressed by monocytes, granulocytes, and in the lungs. Ficolin-1 is found circulating at low concentrations in serum but is regarded primarily as a secretory molecule that exerts its function locally in inflamed tissues.
- Molecular Weight
- 33.11 kDa. Due to glycosylation, the protein migrates to 34-38 kDa based on Tris-Bis PAGE result.
- NCBI Accession
- NP_001994
- Pathways
- Complement System
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