N-Cadherin Protein (AA 160-724) (Fc Tag)
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- Target See all N-Cadherin (CDH2) Proteins
- N-Cadherin (CDH2) (Cadherin 2 (CDH2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 160-724
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This N-Cadherin protein is labelled with Fc Tag.
- Purpose
- Human N Cadherin Protein
- Sequence
- Asp160-Ala724
- Characteristics
- Recombinant Human N Cadherin Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Asp160-Ala724.
- Purity
- > 90 % as determined by Tris-Bis PAGE
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product CDH2 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- N-Cadherin (CDH2) (Cadherin 2 (CDH2))
- Alternative Name
- N Cadherin (CDH2 Products)
- Synonyms
- CD325 Protein, CDHN Protein, CDw325 Protein, NCAD Protein, N-cadherin Protein, cadherin-2 Protein, cdhn Protein, ncad Protein, cdw325 Protein, CDH2 Protein, Cadherin-2 Protein, Ncad Protein, glo Protein, lyr Protein, pac Protein, wu:fb47h04 Protein, cadherin 2 Protein, cadherin 2 S homeolog Protein, cadherin 2, type 1, N-cadherin (neuronal) Protein, CDH2 Protein, cdh2.S Protein, cdh2 Protein, Cdh2 Protein
- Background
- Neural (N)-cadherin is a calcium-dependent single-chain transmembrane glycoprotein that mediates homotypic and heterotypic cell-cell adhesion. As an important member of the cadherin family, N-cadherin plays an important role in the developmental and functional regulation of the nervous system, brain, heart, skeletal muscles, blood vessels and hematopoietic microenvironment.
- Molecular Weight
- 88.56 kDa. Due to glycosylation, the protein migrates to 100-120 kDa based on Tris-Bis PAGE result.
- NCBI Accession
- NP_001783
- Pathways
- Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Synaptic Membrane
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