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SETD7 Protein (AA 1-366) (His tag)

SETD7 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7504524
  • Target See all SETD7 Proteins
    SETD7 (SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-366
    Origin
    • 4
    • 1
    • 1
    Human
    Source
    • 2
    • 1
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This SETD7 protein is labelled with His tag.
    Purpose
    Human SETD7 Protein
    Sequence
    Met1-Lys366
    Characteristics
    Recombinant Human SETD7 Protein is expressed from E.coli with His tag at the N-Terminus.It contains Met1-Lys366.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product SETD7 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    SETD7 (SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))
    Alternative Name
    SETD7 (SETD7 Products)
    Synonyms
    KMT7 Protein, SET7 Protein, SET7/9 Protein, SET9 Protein, set7 Protein, zgc:101860 Protein, zgc:92330 Protein, 1600028F23Rik Protein, H3K4MT Protein, Set7 Protein, Set7/9 Protein, mKIAA1717 Protein, SET domain containing lysine methyltransferase 7 Protein, SET domain containing (lysine methyltransferase) 7 Protein, SETD7 Protein, setd7 Protein, Setd7 Protein
    Background
    SETD7 is a methyltransferase that specifically catalyzes the monomethylation of lysine 4 on histone H3. A variety of studies has revealed the role of SETD7 in posttranslational modifications of non-histone proteins. Aberrant expression of SETD7 has been associated with various diseases, including cancer. As a prognostic marker of breast cancer and a novel antioxidant promoter under oxidative stress in breast cancer, SETD7 is considered a good target for the development of new epigenetic drugs.
    Molecular Weight
    41.68 kDa. The protein migrates to 47-50 kDa based on Tris-Bis PAGE result.
    NCBI Accession
    NP_085151
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