SETD7 Protein (AA 1-366) (His tag)
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- Target See all SETD7 Proteins
- SETD7 (SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-366
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This SETD7 protein is labelled with His tag.
- Purpose
- Human SETD7 Protein
- Sequence
- Met1-Lys366
- Characteristics
- Recombinant Human SETD7 Protein is expressed from E.coli with His tag at the N-Terminus.It contains Met1-Lys366.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product SETD7 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- SETD7 (SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))
- Alternative Name
- SETD7 (SETD7 Products)
- Synonyms
- KMT7 Protein, SET7 Protein, SET7/9 Protein, SET9 Protein, set7 Protein, zgc:101860 Protein, zgc:92330 Protein, 1600028F23Rik Protein, H3K4MT Protein, Set7 Protein, Set7/9 Protein, mKIAA1717 Protein, SET domain containing lysine methyltransferase 7 Protein, SET domain containing (lysine methyltransferase) 7 Protein, SETD7 Protein, setd7 Protein, Setd7 Protein
- Background
- SETD7 is a methyltransferase that specifically catalyzes the monomethylation of lysine 4 on histone H3. A variety of studies has revealed the role of SETD7 in posttranslational modifications of non-histone proteins. Aberrant expression of SETD7 has been associated with various diseases, including cancer. As a prognostic marker of breast cancer and a novel antioxidant promoter under oxidative stress in breast cancer, SETD7 is considered a good target for the development of new epigenetic drugs.
- Molecular Weight
- 41.68 kDa. The protein migrates to 47-50 kDa based on Tris-Bis PAGE result.
- NCBI Accession
- NP_085151
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