TDGF1 Protein (AA 31-172) (His tag)
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- Target See all TDGF1 Proteins
- TDGF1 (Teratocarcinoma-Derived Growth Factor 1 (TDGF1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 31-172
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TDGF1 protein is labelled with His tag.
- Purpose
- Human TDGF1/Cripto Protein
- Sequence
- Leu31-Thr172
- Characteristics
- Recombinant Human TDGF1/Cripto Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu31-Thr172.
- Purity
- > 95 % as determined by Tris-Bis PAGE
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product TDGF1 Protein
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Teratocarcinoma-Derived Growth Factor 1 (TDGF1) (AA 31-188) protein (GST tag)
TDGF1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Teratocarcinoma-Derived Growth Factor 1 (TDGF1) protein (Fc Tag)TDGF1 Origin: Rat Host: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
Teratocarcinoma-Derived Growth Factor 1 (TDGF1) (AA 31-150) protein (His tag)Crystallography grade TDGF1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Teratocarcinoma-Derived Growth Factor 1 (TDGF1) (AA 18-134) protein (His tag)Crystallography grade TDGF1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Teratocarcinoma-Derived Growth Factor 1 (TDGF1) (AA 32-150), (partial) protein (GST tag)TDGF1 Origin: Human Host: Escherichia coli (E. coli) Recombinant 90 % SDS, ELISA
Teratocarcinoma-Derived Growth Factor 1 (TDGF1) (AA 32-150), (partial) protein (His tag)TDGF1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- TDGF1 (Teratocarcinoma-Derived Growth Factor 1 (TDGF1))
- Alternative Name
- TDGF1 (TDGF1 Products)
- Synonyms
- CR Protein, CRGF Protein, CRIPTO Protein, CR1 Protein, cripto Protein, cb85 Protein, tdgf1 Protein, wu:fe01d04 Protein, zgc:109829 Protein, Cripto-1 Protein, cr1 Protein, cr1a Protein, frl-1 Protein, frl1 Protein, xcr1 Protein, TDGF1 Protein, tdgf3 Protein, cripto-3 Protein, teratocarcinoma-derived growth factor 1 Protein, teratocarcinoma-derived growth factor 1, member 3 L homeolog Protein, teratocarcinoma-derived growth factor 1, member 1 Protein, TDGF1 Protein, Tdgf1 Protein, tdgf1 Protein, tdgf1.3.L Protein, tdgf1.1 Protein
- Background
- TDGF1 (CRIPTO) is a member of the epidermal growth factor-Cripto-1/FRL-1/Cryptic (EGF/CFC) gene family and an obligate co-receptor involved in NODAL signaling, a developmental program implicated in midline, forebrain, and left-right axis development in model organisms. Cripto-1 is enriched in a subpopulation of embryonal, melanoma, prostate, and pancreatic cancer cells that possess stem-like characteristics. Therefore, Cripto-1 may play a role during developmental EMT, and it may also be involved in the reprogramming of differentiated tumor cells into cancer stem cells through the induction of an EMT program.
- Molecular Weight
- 16.92 kDa. Due to glycosylation, the protein migrates to 23-30 kDa based on Tris-Bis PAGE result.
- UniProt
- P13385
- Pathways
- EGFR Signaling Pathway
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