Uromodulin Protein (UMOD) (AA 25-587) (His tag)
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- Target See all Uromodulin (UMOD) Proteins
- Uromodulin (UMOD)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 25-587
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Uromodulin protein is labelled with His tag.
- Sequence
- Asp25-Phe587
- Characteristics
- A DNA sequence encoding theHuman THP protein (P07911) (Asp25-Phe587) was expressed with a N-His.
- Purity
- >85 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product UMOD Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- Uromodulin (UMOD)
- Alternative Name
- THP (UMOD Products)
- Synonyms
- ADMCKD2 Protein, FJHN Protein, HNFJ Protein, HNFJ1 Protein, MCKD2 Protein, THGP Protein, THP Protein, urehr4 Protein, uromodulin Protein, UMOD Protein, Umod Protein
- Background
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Background: Functions in biogenesis and organization of the apical membrane of epithelial cells of the thick ascending limb of Henle's loop (TALH), where it promotes formation of complex filamentous gel-like structure that may play a role in the water barrier permeability (Probable). May serve as a receptor for binding and endocytosis of cytokines (IL-1, IL-2) and TNF.Facilitates neutrophil migration across renal epithelia.
Synonym: Tamm-Horsfall urinary glycoprotein
- Molecular Weight
- 61.4 kDa
- UniProt
- P07911
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