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Uromodulin Protein (UMOD) (AA 25-587) (His tag)

UMOD Origin: Human Host: Escherichia coli (E. coli) Recombinant >85 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7505005
  • Target See all Uromodulin (UMOD) Proteins
    Uromodulin (UMOD)
    Protein Type
    Recombinant
    Protein Characteristics
    AA 25-587
    Origin
    • 7
    • 3
    • 3
    • 3
    • 1
    • 1
    Human
    Source
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This Uromodulin protein is labelled with His tag.
    Sequence
    Asp25-Phe587
    Characteristics
    A DNA sequence encoding theHuman THP protein (P07911) (Asp25-Phe587) was expressed with a N-His.
    Purity
    >85 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product UMOD Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    12 months
  • Target
    Uromodulin (UMOD)
    Alternative Name
    THP (UMOD Products)
    Synonyms
    ADMCKD2 Protein, FJHN Protein, HNFJ Protein, HNFJ1 Protein, MCKD2 Protein, THGP Protein, THP Protein, urehr4 Protein, uromodulin Protein, UMOD Protein, Umod Protein
    Background

    Background: Functions in biogenesis and organization of the apical membrane of epithelial cells of the thick ascending limb of Henle's loop (TALH), where it promotes formation of complex filamentous gel-like structure that may play a role in the water barrier permeability (Probable). May serve as a receptor for binding and endocytosis of cytokines (IL-1, IL-2) and TNF.Facilitates neutrophil migration across renal epithelia.

    Synonym: Tamm-Horsfall urinary glycoprotein

    Molecular Weight
    61.4 kDa
    UniProt
    P07911
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