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THAP1 Protein (AA 1-81) (His tag)

THAP1 Origin: Human Host: Escherichia coli (E. coli) Recombinant >80 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7505021
  • Target See all THAP1 Proteins
    THAP1 (THAP Domain Containing, Apoptosis Associated Protein 1 (THAP1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-81
    Origin
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 5
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This THAP1 protein is labelled with His tag.
    Sequence
    Met1-Phe81
    Characteristics
    A DNA sequence encoding theHuman THAP1 protein (Q9NVV9) (Met1-Phe81) was expressed with a N-His.
    Purity
    >80 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product THAP1 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    12 months
  • Target
    THAP1 (THAP Domain Containing, Apoptosis Associated Protein 1 (THAP1))
    Alternative Name
    THAP1 (THAP1 Products)
    Synonyms
    THAP1 Protein, thap1-a Protein, DYT6 Protein, 4833431A01Rik Protein, AW490810 Protein, zgc:136597 Protein, THAP domain containing, apoptosis associated protein 1 Protein, THAP domain containing 1 Protein, THAP domain containing, apoptosis associated protein 1 L homeolog Protein, thap1 Protein, THAP1 Protein, thap1.L Protein, Thap1 Protein
    Background

    Background: DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes, including RRM1. Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. May also have pro-apoptotic activity by potentiating both serum-withdrawal and TNF-induced apoptosis.

    Synonym: THAP domain-containing protein 1

    Molecular Weight
    9.5 kDa
    UniProt
    Q9NVV9
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