THAP1 Protein (AA 1-81) (His tag)
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- Target See all THAP1 Proteins
- THAP1 (THAP Domain Containing, Apoptosis Associated Protein 1 (THAP1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-81
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This THAP1 protein is labelled with His tag.
- Sequence
- Met1-Phe81
- Characteristics
- A DNA sequence encoding theHuman THAP1 protein (Q9NVV9) (Met1-Phe81) was expressed with a N-His.
- Purity
- >80 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product THAP1 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- THAP1 (THAP Domain Containing, Apoptosis Associated Protein 1 (THAP1))
- Alternative Name
- THAP1 (THAP1 Products)
- Synonyms
- THAP1 Protein, thap1-a Protein, DYT6 Protein, 4833431A01Rik Protein, AW490810 Protein, zgc:136597 Protein, THAP domain containing, apoptosis associated protein 1 Protein, THAP domain containing 1 Protein, THAP domain containing, apoptosis associated protein 1 L homeolog Protein, thap1 Protein, THAP1 Protein, thap1.L Protein, Thap1 Protein
- Background
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Background: DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes, including RRM1. Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. May also have pro-apoptotic activity by potentiating both serum-withdrawal and TNF-induced apoptosis.
Synonym: THAP domain-containing protein 1
- Molecular Weight
- 9.5 kDa
- UniProt
- Q9NVV9
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