NT-ProBNP Protein (AA 27-76) (GST tag)

Catalog No. ABIN7505496

Product Details

Target: NT-ProBNP (Pro-Brain Natriuretic Peptide (NT-ProBNP) (NT-ProBNP))

Protein Type: Recombinant

Protein Characteristics: AA 27-76

Origin: Rat

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This NT-ProBNP protein is labelled with GST tag.

Sequence: His27-Arg76

Characteristics: A DNA sequence encoding the Rat NT-proBNP protein (P13205) (His27-Arg76) was expressed with a GST.

Purity: >95 % as determined by reducing SDS-PAGE.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: NT-ProBNP (Pro-Brain Natriuretic Peptide (NT-ProBNP) (NT-ProBNP))

Alternative Name: NT-proBNP (NT-ProBNP Products)

Background:

Background: NT-proBNP, or Brain Natriuretic Peptide, is a hormone expressed by cardiomyocytes by the gene NPPB. NT-proBNP is synthesized as a 134- amino acid preprohormone (prepro-BNP), subsequent removal of a 25 amino acid signal peptide forms pro-BNP, which is stored intracellularly. Pro-BNP is secreted as an inactive prohormone and cleavage by furin or corin forms NT-pro-BNP and the active 32- amino acid BNP-32 peptide. BNP may function as a paracrine antifibrotic factor in the heart, as well as have a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion.

Synonym: Natriuretic peptides B, ANFB_RAT, Nppb,Brain natriuretic factor prohormone, preproBNP, proBNP,Gamma-brain natriuretic peptide, Iso-ANP,

Molecular Weight: 30.39 kDa

UniProt: P13205