CDNF Protein (AA 25-187) (His tag)
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- Target See all CDNF Proteins
- CDNF (Cerebral Dopamine Neurotrophic Factor (CDNF))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 25-187
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CDNF protein is labelled with His tag.
- Sequence
- Gln25-Leu187
- Characteristics
- Recombinant Human Conserved Dopamine Neurotrophic Factor is produced by our Mammalian expression system and the target gene encoding Gln25-Leu187 is expressed with a 6His tag at the C-terminus.
- Purity
- >95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- <1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product CDNF Protein
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Cerebral Dopamine Neurotrophic Factor (CDNF) (AA 25-187) protein (His tag)
CDNF Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Cerebral Dopamine Neurotrophic Factor (CDNF) protein (His tag)CDNF Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
Cerebral Dopamine Neurotrophic Factor (CDNF) (AA 25-187) protein (His tag)Crystallography grade CDNF Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Cerebral Dopamine Neurotrophic Factor (CDNF) (AA 25-187) protein (His tag)Crystallography grade CDNF Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Expiry Date
- 12 months
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- Target
- CDNF (Cerebral Dopamine Neurotrophic Factor (CDNF))
- Alternative Name
- CDNF (CDNF Products)
- Synonyms
- ARMETL1 Protein, 9330140G23 Protein, Armetl1 Protein, cerebral dopamine neurotrophic factor Protein, CDNF Protein, Cdnf Protein
- Background
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Background: erebral Dopamine Neurotrophic Factor (CDNF), also known as ARMETL1 (ARMET-like protein 1), is a secreted protein with eight conserved cysteine residues.It is belongs to the ARMET family. CDNF/ARMETL1 is a evolutionary conserved protein which can protect and restore the function of dopaminergic neurons in the rat model of Parkinson's disease, suggesting that CDNF might be beneficial for the treatment of Parkinson's disease. CDNF is widely expressed in neurons in several brain regions including cerebral cortex, hippocampus, substantia nigra, striatum and cerebellum. Human CDNF is glycosylated and secreted from transiently transfected cells. CDNF promotes the survival, growth, and function of dopamine-specific neurons and is expressed in brain regions that undergo cocaine-induced neuroplasticity.
Synonym: Cerebral dopamine neurotrophic factor, ARMET-like protein 1, Conserved dopamine neurotrophic factor, ARMETL1
- Molecular Weight
- 21.7 kDa
- UniProt
- Q49AH0
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