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CEACAM3 Protein (His tag)

CEACAM3 Origin: Human Host: HEK-293 Cells Recombinant > 92 % by SDS-PAGE. Active
Catalog No. ABIN7534052
  • Target See all CEACAM3 Proteins
    CEACAM3 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3 (CEACAM3))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 7
    • 3
    Human
    Source
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CEACAM3 protein is labelled with His tag.
    Purpose
    Active Recombinant Human CEACAM3/CD66d Protein
    Sequence
    MGPPSASPHR ECIPWQGLLL TASLLNFWNP PTTAKLTIES MPLSVAEGKE VLLLVHNLPQ HLFGYSWYKG ERVDGNSLIV GYVIGTQQAT PGAAYSGRET IYTNASLLIQ NVTQNDIGFY TLQVIKSDLV NEEATGQFHV YQENAPGLPV GAVAG
    Specificity
    Met1-Gly155
    Purity
    > 92 % by SDS-PAGE.
    Sterility
    0.22 μm filtered
    Endotoxin Level
    < 0.1 EU/μg of the protein by LAL method.
    Biological Activity Comment
    Measured by its binding ability in a functional ELISA. Immobilized Human CEACAM3 at 1μg/mL (100 μL/well) can bind CEACAM3 Mouse mAb with a linear range of 0.1-2.7 ng/mL.
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  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    Buffer
    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store the lyophilized protein at -20°C to -80 °C for long term.
    After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
  • Target
    CEACAM3 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3 (CEACAM3))
    Alternative Name
    CEACAM3/CD66d (CEACAM3 Products)
    Synonyms
    CD66D Protein, CEA Protein, CGM1 Protein, W264 Protein, W282 Protein, CGM4AA Protein, Cea Protein, Ceacam5 Protein, Cear Protein, Cgm1 Protein, Cgm4 Protein, RATCEAA Protein, RATCGM4AA Protein, EG384557 Protein, Psg24 Protein, cea12 Protein, carcinoembryonic antigen related cell adhesion molecule 3 Protein, carcinoembryonic antigen-related cell adhesion molecule 3 Protein, CEACAM3 Protein, Ceacam3 Protein
    Background

    Description: The protein encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described.

    Name: CEACAM3,CD66D,CEA,CGM1,W264,W282

    Gene ID
    1084
    UniProt
    P40198
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