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CCL6 Protein (His tag)

CCL6 Origin: Mouse Host: HEK-293 Cells Recombinant > 97 % by SDS-PAGE.
Catalog No. ABIN7536237
  • Target See all CCL6 Proteins
    CCL6 (Chemokine (C-C Motif) Ligand 6 (CCL6))
    Protein Type
    Recombinant
    Origin
    • 6
    • 4
    Mouse
    Source
    • 5
    • 3
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CCL6 protein is labelled with His tag.
    Purpose
    Recombinant Mouse CCL6 Protein
    Sequence
    GLIQEMEKED RRYNPPIIHQ GFQDTSSDCC FSYATQIPCK RFIYYFPTSG GCIKPGIIFI SRRGTQVCAD PSDRRVQRCL STLKQGPRSG NKVIA
    Specificity
    Gly22 - Ala116
    Purity
    > 97 % by SDS-PAGE.
    Sterility
    0.22 μm filtered
    Endotoxin Level
    <1EU/μg
    Top Product
    Discover our top product CCL6 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    Concentration
    1.3 mg/mL
    Buffer
    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
  • Target
    CCL6 (Chemokine (C-C Motif) Ligand 6 (CCL6))
    Alternative Name
    CCL6 (CCL6 Products)
    Synonyms
    MRP-1 Protein, Scya6 Protein, c10 Protein, Abcc1a Protein, Avcc1a Protein, Mrp Protein, Mrp1 Protein, Mrp-1 Protein, Scay6 Protein, chemokine (C-C motif) ligand 6 Protein, ATP binding cassette subfamily C member 1 Protein, Ccl6 Protein, Abcc1 Protein
    Background

    Description: Chemokine (C-C motif) ligand 6 (CCL6), also known as C-C chemokine C10 has only been identified in rodents, which is a small cytokine belonging to the CC chemokine family, beta-chemokine subfamily. C-C chemokine C10 is involved in the chronic stages of host defense reactions. C10 chemokine rapidly promotes disease resolution in the cecal ligation and puncture (CLP) model through its direct effects on the cellular events critically involved in host defense during septic peritonitis. CCL6 appears to contribute to the macrophage infiltration that is independent of other CC chemokines. C10 is a prominent chemokine expressed in the central nervous system in experimental inflammatory demyelinating disease, also acts as a potent chemotactic factor for the migration of these leukocytes to the brain. CCL6 may be a mediator released by microglia for cell-cell communication under physiological as well as pathological conditions of CNS. Additionally, the chemokine CCL6 may alter tumor behavior by relieving its growth factor dependency and by promoting invasiveness as a result of local tissue apoptosis.

    Name: c10, MRP-1, Scya6,CCL6

    Gene ID
    20305
    UniProt
    P27784
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