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IL36A/IL1F6 Protein (His tag)

IL1F6 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS-PAGE.
Catalog No. ABIN7533752
  • Target See all IL36A/IL1F6 (IL1F6) Proteins
    IL36A/IL1F6 (IL1F6) (Interleukin 1 Family, Member 6 (IL1F6))
    Protein Type
    Recombinant
    Origin
    • 9
    • 5
    Human
    Source
    • 10
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This IL36A/IL1F6 protein is labelled with His tag.
    Purpose
    Recombinant Human IL-36 alpha/IL-1F6 Protein
    Sequence
    MEKALKIDTP QQGSIQDINH RVWVLQDQTL IAVPRKDRMS PVTIALISCR HVETLEKDRG NPIYLGLNGL NLCLMCAKVG DQPTLQLKEK DIMDLYNQPE PVKSFLFYHS QSGRNSTFES VAFPGWFIAV SSEGGCPLIL TQELGKANTT DFGLTMLF
    Specificity
    Met1-Phe158
    Purity
    > 95 % by SDS-PAGE.
    Sterility
    0.22 μm filtered
    Endotoxin Level
    < 1.0 EU/μg of the protein by LAL method.
    Top Product
    Discover our top product IL1F6 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    Buffer
    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store the lyophilized protein at -20°C to -80 °C for long term.
    After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
  • Target
    IL36A/IL1F6 (IL1F6) (Interleukin 1 Family, Member 6 (IL1F6))
    Alternative Name
    IL-36 alpha/IL-1F6 (IL1F6 Products)
    Synonyms
    Il1f6 Protein, Fil1 Protein, IL-1H1 Protein, IL1RP2 Protein, Il1f9 Protein, Il36a Protein, FIL1 Protein, FIL1(EPSILON) Protein, FIL1E Protein, IL-1F6 Protein, IL1(EPSILON) Protein, IL1F6 Protein, interleukin 36, alpha Protein, interleukin 1 family, member 6 (epsilon) Protein, interleukin 1 family, member 6 Protein, interleukin 36 alpha Protein, Il36a Protein, IL1F6 Protein, IL36A Protein, Il1f6 Protein
    Background

    Description: Interleukin-1 family member 6 (IL-1F6), also known as interleukin 36, alpha (IL36A), is a pro-inflammatory cytokine which plays an important role in innate and adaptive immunity.IL-1F6 can activate NF-kappa-B and MAPK signaling pathways to generate an inflammatory response. The encoded protein functions primarily in skin and demonstrates increased expression in psoriasis. In addition, decreased expression of this protein has been linked to a poor prognosis in both hepatocellular carcinoma and colorectal cancer patients.

    Name: IL36A,FIL1,FIL1(EPSILON),FIL1E,IL-1F6,IL1(EPSILON),IL1F6

    Gene ID
    27179
    UniProt
    Q9UHA7
    Pathways
    Cancer Immune Checkpoints
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