PPIA Protein

Catalog No. ABIN7533732

Product Details

Target: PPIA (Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purpose: Recombinant Human PPIase A/PPIA Protein

Sequence: MVNPTVFFDI AVDGEPLGRV SFELFADKVP KTAENFRALS TGEKGFGYKG SCFHRIIPGF MCQGGDFTRH NGTGGKSIYG EKFEDENFIL KHTGPGILSM ANAGPNTNGS QFFICTAKTE WLDGKHVVFG KVKEGMNIVE AMERFGSRNG KTSKKITIAD CGQLE

Specificity: Met1-Glu165

Purity: > 97 % by SDS-PAGE.

Sterility: 0.22 μm filtered

Endotoxin Level: < 1.0 EU/μg of the protein by LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Buffer: Lyophilized from a 0.22 μm filtered solution of 50 mM Tris, 150 mM NaCl, pH 8.0.

Storage: -20 °C,-80 °C

Storage Comment: Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.

Target Details

Target: PPIA (Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA))

Alternative Name: PPIase A/PPIA (PPIA Products)

Synonyms: Cyp1 Protein, PPIA-2 Protein, fa93g09 Protein, ppia Protein, wu:fa93g09 Protein, wu:fb05e11 Protein, wu:fb13h02 Protein, wu:fb15a05 Protein, CYPA Protein, CypA Protein, Cypa Protein, CYPH Protein, CYCA Protein, CyP-A Protein, MGC75715 Protein, 2700098C05 Protein, Cphn Protein, CyP-18 Protein, MT-ND1 Protein, MTND1 Protein, NADH1 Protein, ND1 Protein, cypA Protein, PPIase A Protein, ppial Protein, wu:fj18g05 Protein, zgc:73102 Protein, zgc:86688 Protein, peptidylprolyl isomerase A Protein, peptidylprolyl isomerase Aa (cyclophilin A) Protein, peptidylprolyl isomerase A (cyclophilin A) L homeolog Protein, cyclophilin A Protein, cyclophilin a Protein, peptidylprolyl isomerase A (cyclophilin A) Protein, peptidylprolyl isomerase Ab (cyclophilin A) Protein, PPIA Protein, ppiaa Protein, ppia.L Protein, Cypa Protein, CNB01230 Protein, CNB01290 Protein, Tc00.1047053506925.300 Protein, Tb11.03.0250 Protein, CYPA Protein, Ppia Protein, ppia Protein, ppiab Protein

Background:

Description: This protein is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. The protein is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions.

Name: PPIA,CYPA,CYPH,HEL-S-69p

Gene ID: 5478

UniProt: P62937